Results 51 to 60 of about 359,102 (245)

Health system changes needed to support people consulting general practice out of hours services in Ireland

open access: yesInternational Journal of Mental Health Systems, 2018
Background Mental illness acts as a barrier to accessing and obtaining effective medical care. It has been shown that out of hours services are an important first stop for emergency care for people experiencing mental health difficulties. However, little
C. Collins   +3 more
doaj   +1 more source

Irish language, Irish nation

open access: yes, 2014
Nearly half the country speaks Irish. Erroneous as this statement may appear, results from the 2011 census indicate that 42 per cent of the population of the Republic of Ireland can speak Irish.
Watson, Iarfhlaith, Iarfhlaith Watson
core   +1 more source

Dynamic Fluorescence Modulation via Light‐Driven Competitive Protonation

open access: yesAdvanced Optical Materials, EarlyView.
A two‐component molecular system demonstrates reversible, light‐driven fluorescence write–erase cycling and thermal imaging. Illumination of a merocyanine photoacid transfers a proton to a highly efficient fluorescent pyridinium dye, switching its emission color; thermal relaxation reverses the process in the dark.
Serena X. Liu   +10 more
wiley   +1 more source

Genetic benefits of genomic selection breeding programmes considering foreign sire contributions

open access: yesGenetics Selection Evolution, 2019
Background In modern dairy breeding programmes, high contributions from foreign sires are nearly always present. Genotyping, and therefore genomic selection (GS), concern only a subpopulation of the breeding programme’s wider dairy population.
Daragh Matthews   +4 more
doaj   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

open access: yesAdvanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Interpretable Machine Learning Framework for Nb─Si Based Alloy Design with Enhanced Fracture Toughness

open access: yesAdvanced Science, EarlyView.
An interpretable machine learning framework integrating SHAP and PDP analysis identifies critical design descriptors from 139 physicochemical features for Nb─Si alloys. The framework achieves <7% prediction error and guides the discovery of Nb38.5Ti38.5Si3Zr18V2 alloy with 22.791 MPa·m1/2 fracture toughness, breaking the 20 MPa·m1/2 barrier.
Dezhi Chen   +7 more
wiley   +1 more source

The Irish Maritime Transport Economist Volume 3

open access: yes, 2006
The Irish Maritime Development Office (IMDO) of the Marine Institute publishes the Irish Maritime Transport Economist each year to provide a descriptive statistical analysis of the Irish ports and shipping services sector, as well as the many factors ...
Irish Maritime Development Office
core  

Charting the Future of Stereoselective Carbohydrate Synthesis: The Essential Role of Cross‐Disciplinary Innovation

open access: yesAdvanced Science, EarlyView.
Cross‐disciplinary endeavors are blossoming across the broad chemical sciences. This perspective provides a glimpse into the rewarding interdisciplinary journey taken by the Charles Loh research group in pioneering the σ‐hole based catalytic glycosylation strategy.
Charles C. J. Loh
wiley   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

open access: yesAdvanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang   +12 more
wiley   +1 more source

A national model of remote care for assessing and providing opioid agonist treatment during the COVID-19 pandemic: a report

open access: yesHarm Reduction Journal, 2020
Background Health services globally are struggling to manage the impact of COVID-19. The existing global disease burden related to opioid use is significant.
Des Crowley, Ide Delargy
doaj   +1 more source

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