Results 161 to 170 of about 3,761,877 (195)
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray +2 more
wiley +1 more source
Researching Attitude–Identity Dynamics to Understand Social Conflict and Change
Abstract Societies undergo constant change, manifested in various ways such as technological developments, economic transitions, reorganization of cultural values and beliefs, or changes in social structures. Individuals play an active role in shaping social and societal change by interactively negotiating its manifestation.
Adrian Lüders +4 more
wiley +1 more source
ABSTRACT Despite the variety of populist manifestations, little research has dedicated itself to exploring this variation within and between individuals. Building on a discursive tradition, we propose that individuals meaningfully differ in how they construct the populist group of ‘the people’. Across three studies, we developed a popular inclusion and
Joseph D. Foley +2 more
wiley +1 more source
ABSTRACT Many important historical and contemporary ethical debates (e.g., on slavery, abortion and environmental protection) reflect disagreements about what we owe to different groups of individuals. Recent work in moral psychology has uncovered a seemingly replicable hierarchy of moral concern, but these studies were conducted in a few countries ...
Işıl Ayça Akkuş +4 more
wiley +1 more source
Abstract Objective This study was undertaken to estimate the prevalence and characterize the semiology of co‐occurring functional/dissociative seizures (FDSs) and identify clinical features potentially associated with the development of video‐electroencephalography (video‐EEG)‐diagnosed FDSs in patients with idiopathic generalized epilepsy (IGE ...
Javier Peña‐Ceballos +13 more
wiley +1 more source
Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis
Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx +192 more
wiley +1 more source
Absence seizures: Update on signaling mechanisms and networks
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Genetic testing practices across European epilepsy centers: An ERN EpiCARE survey
Abstract Objective Genetic testing plays an increasing role in the diagnostic pathway for rare and complex epilepsies. However, significant heterogeneity persists in access, implementation, and interpretation across Europe. This study aimed to assess genetic testing practices, accessibility, and challenges across expert epilepsy centers within the ...
Sébile Tchaicha +11 more
wiley +1 more source
Abstract Objective To evaluate the effectiveness and tolerability of cenobamate in patients with a significant reduction in concomitant antiseizure medication (ASM) in European cenobamate Early Access Programs (EAPs). Method Anonymized patient data from real‐world studies/registries associated with European cenobamate EAPs were pooled.
Vicente Villanueva +25 more
wiley +1 more source
ABSTRACT Objectives Despite increasing evidence of the physical and psychosocial impairments associated with Avoidant/Restrictive Food Intake Disorder (ARFID), there are currently no national guidelines for its assessment and treatment. In the absence of such guidance, it is crucial to understand the experiences of healthcare professionals (HCPs ...
Sandra‐Eve Bamigbade +2 more
wiley +1 more source

