Results 61 to 70 of about 31,817 (293)

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen   +2 more
wiley   +1 more source

Imagerie de la torsion ovarienne chez la jeune fille : à propos de 8 observations et revue de la littérature

open access: yesPAMJ Clinical Medicine, 2020
La torsion ovarienne est une cause rare de douleur abdominale aiguë chez l´enfant, elle constitue une véritable urgence diagnostique et thérapeutique. Le tableau clinique ainsi que la présentation radiologique est non spécifique.
Souley Abdoulaziz   +7 more
doaj   +1 more source

Supercritical Fluid Chromatography for Expedited Sample Clean‐Up in Isotope Ratio Mass Spectrometry Including Cholesterol as New Endogenous Reference Compound

open access: yesDrug Testing and Analysis, EarlyView.
Supercritical fluid chromatography was employed in the sample preparation for IRMS determinations in sports drug testing for the first time and the developed method was successfully validated. Cholesterol (CHOL) was introduced as a novel endogenous reference compound and population‐based Δ‐values were established as shown here.
Thomas Piper, Jana Drewes, Mario Thevis
wiley   +1 more source

Simultaneous Detection of Steroid Esters and Multi‐Class Substances in Dried Blood Spots by LC‐HRMS/MS From a Single Spot for Human Doping Control

open access: yesDrug Testing and Analysis, EarlyView.
A validated LC‐HRMS/MS method enabled, for the first time, the comprehensive detection of steroid esters and multi‐class menu substances from a single dried blood spot. Following extraction, the resulting extract is split into two aliquots, reducing sample consumption and simplifying the analytical workflow.
Panagiotis Sakellariou   +4 more
wiley   +1 more source

A Single‐Aliquot Strategy for Simultaneous Carbon Isotope Confirmation of 6‐Oxo‐Androstenedione and Testosterone Misuse in Doping Control

open access: yesDrug Testing and Analysis, EarlyView.
This method enables simultaneous carbon isotope confirmation of 6‐oxo‐androstenedione and testosterone markers from a single urine aliquot, using bench‐top extraction, two preparative HPLC steps with intermediate acetylation, and GC/C/IRMS analysis. It was fully validated according to WADA requirements, and real samples demonstrated its fitness for ...
Fábio Azamor de Oliveira   +7 more
wiley   +1 more source

A Framework for Effective Bt Maize IRM Programs: Incorporation of Lessons Learned From Busseola fusca Resistance Development

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Bt maize is genetically engineered to express insecticidal proteins from the bacterium Bacillus thuringiensis. Bt maize is used extensively by South African farmers to reduce yield losses caused by lepidopteran larvae.
Gustav Bouwer
doaj   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo   +7 more
wiley   +1 more source

Predictors of the Dose-Effect Relationship regarding Unilateral Inferior Rectus Muscle Recession in Patients with Thyroid Eye Disease

open access: yesInternational Journal of Endocrinology, 2015
Purpose. To evaluate whether inferior rectus muscle (IRM) thickness, the degree of adipose change in the IRM, smoking status, and the previous history of orbital radiotherapy can predict the dose-effect relationship regarding unilateral IRM recession in ...
Yasuhiro Takahashi, Hirohiko Kakizaki
doaj   +1 more source

Compare the accuracy and precision of Coulter LH780, Mindray BC-6000 Plus, and Sysmex XN-9000 with the international reference flow cytometric method in platelet counting.

open access: yesPLoS ONE, 2019
ObjectiveThe aim of this study is to evaluate the performance of different platelet counting methods (optical, impedance, fluorescence and hand counting) applied in different analysers by comparing with the international flow cytometric reference method (
Yi Sun   +9 more
doaj   +1 more source

Une cause rare d'exophtalmie: l'hémangiome caverneux intraorbitaire (à propos d'un cas)

open access: yesThe Pan African Medical Journal, 2017
L'hémangiome caverneux est la plus fréquente des tumeurs vasculaires bénignes primitives de l'orbite chez l'adulte; l'âge moyen de découverte est de 42 ans avec une prédilection féminine.
Abderrazzak El Saqui   +4 more
doaj   +1 more source

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