Results 41 to 50 of about 6,184 (250)

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Modelling Sustainability Performance in Manufacturing Companies

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Nowadays, organisations need to operate with economic, social and environmental goals in mind. Indices objectively quantify such goals; hence, an organisation can develop and compare policies based on future index values. We propose a system dynamics‐based model of a manufacturing company that frames its operations in terms of a set of easily ...
Harol Andrey Avila‐Choconta, Liliana Ruiz‐Acosta, David Andrés Camargo‐Mayorga, Mario Andrés Muñoz   +3 more
wiley   +1 more source

Detection of Testosterone Esters in Urine: Evidence of Trace‐Level Detectability in Doping Control Samples

Drug Testing and Analysis, EarlyView.
An ultrasensitive LC‐MS/MS method for detecting testosterone esters (T‐esters) in urine at sub–pg/mL levels is presented. This approach, employing Girard P derivatization, provides the first evidence of T‐esters' trace‐level detectability in human urine.
Daniel Pecher, Guro Forsdahl, Biljana Stojanovic, Günter Gmeiner   +3 more
wiley   +1 more source

Analisis Pemrograman Preservasi Jalan dengan Strategi Penanganan Sementara (Back-fall Strategy) Skala Jaringan menggunakan Metode IRMS V.3 dan MEPDG 2015

Jurnal Teknik Sipil
Abstrak Penelitian ini bertujuan membandingkan akurasi metode prediksi kondisi jalan antara MEPDG 2015 dan IRMS V.3 sebagai dasar pemrograman preservasi jalan pada skala jaringan.
Gita Yuliani, Eri Susanto Hariyadi, Ade Sjafruddin   +2 more
doaj   +1 more source

Rapid measurement of plasma free fatty acid concentration and isotopic enrichment using LC/MS

Journal of Lipid Research, 2010
Measurements of plasma free fatty acids (FFA) concentration and isotopic enrichment are commonly used to evaluate FFA metabolism. Until now, gas chromatography-combustion-isotope ratio mass spectrometry (GC/C/IRMS) was the best method to measure isotopic
Xuan-Mai T. Persson, Agnieszka Urszula Błachnio-Zabielska, Michael D. Jensen   +2 more
doaj   +1 more source

Dietary partitioning mediates species coexistence in the high seas area of northwest Pacific

Ecography, EarlyView.
Niche partitioning, manifesting along various axes of the ecological niche, is a fundamental mechanism mediating species coexistence in a system. However, the emergence of many species in marine ecosystems would face considerable constraints in achieving coexistence through spatiotemporal differentiation mechanisms under the framework of niche ...
Na Zang, Bilin Liu, Wenjun Zheng, Yushuang Luo, André E. Punt, Xinjun Chen, Dongming Lin   +6 more
wiley   +1 more source

Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1237-1245, April 2025.
Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri, Ahmad Gharaibeh, Lubika Nkashama, Abdelrahman Abushouk, Osama Abushawer, Amir Mehdizadeh‐Shrifi, Bianca Honnekeri, Cassandra Calabrese, Venu Menon, Pauline Funchain, Patrick Collier, Diego Sadler, Rohit Moudgil   +12 more
wiley   +1 more source

Mechanical Behaviour of Vacuum‐Infused GFRP Composites at Elevated Temperatures—Influence of Fibre Architecture

Fire and Materials, EarlyView.
ABSTRACT This study addresses the influence of fibre architecture on the mechanical properties of vacuum‐infused glass fibre reinforced polymer (GFRP) composites at elevated temperatures (ET). Laminates with three different fibre configurations—unidirectional (UD), bidirectional 0°/90° cross‐ply (BD), and ±45° off‐axis angle‐ply (OA) – were tested in ...
Eloísa Castilho, João P. Firmo, Mário Garrido, João R. Correia, Afonso Ataíde   +4 more
wiley   +1 more source

Half a Century of Per‐ and Polyfluoroalkyl Substances in Northern Gannet Eggs: Impact of Regulations

Journal of Applied Toxicology, EarlyView.
ABSTRACT Per‐ and polyfluoroalkyl substances (PFAS), known as “forever chemicals”, are persistent organic pollutants that have been widely used in the industry across the globe for many decades. Their chemical stability, bioaccumulation, and toxicity pose major environmental and health risks. This study examines temporal trends in the concentrations of
Anaïs Fournier, Anaïs Kerric, Raphaël A. Lavoie   +2 more
wiley   +1 more source

Modelling Critical Impeding Factors of Gamification Adoption: An ISM‐MICMAC Analysis

Global Business and Organizational Excellence, EarlyView.
ABSTRACT Gamification is a transformative technology that attracts consumers and motivates them toward desired actions through fun and engagement. Despite its growing popularity and influence on user behavior, gamification faces significant challenges in acceptance and implementation due to behavioral, technological, economic, and regulatory factors ...
Wamika Sharma, Dinesh Kumar, Aastha Verma, Rodney Lim, Garima Gupta   +4 more
wiley   +1 more source