Results 71 to 80 of about 446,236 (313)

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

HmuY proteins of the Porphyromonas genus show diversity in heme-binding properties

Frontiers in Cellular and Infection Microbiology
IntroductionBacteria of the Porphyromonas genus, belonging to the Bacteroidota phylum, colonize various host niches in health and disease. As heme auxotrophs, they rely on heme uptake for iron and protoporphyrin IX.
Michał Śmiga, Teresa Olczak
doaj   +1 more source

Prediction of DtxR regulon: Identification of binding sites and operons controlled by Diphtheria toxin repressor in Corynebacterium diphtheriae

BMC Microbiology, 2004
Background The diphtheria toxin repressor, DtxR, of Corynebacterium diphtheriae has been shown to be an iron-activated transcription regulator that controls not only the expression of diphtheria toxin but also of iron uptake genes.
Hasnain Seyed, Chakhaiyar Prachee, Ranjan Sarita, Yellaboina Sailu, Ranjan Akash   +4 more
doaj   +1 more source

Structure and molecular evolution of CDGSH iron-sulfur domains. [PDF]

PLoS ONE, 2011
The recently discovered CDGSH iron-sulfur domains (CISDs) are classified into seven major types with a wide distribution throughout the three domains of life.
Jinzhong Lin, Liman Zhang, Shaomei Lai, Keqiong Ye   +3 more
doaj   +1 more source

Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide β-amyloid (1-42) [PDF]

, 2014
For decades, a link between increased levels of iron and areas of Alzheimer's disease (AD) pathology has been recognized, including AD lesions comprised of the peptide β-amyloid (Aβ).
van der Laan, Gerrit, Jenkins, C.A., Collingwood, Joanna F., Everett, James, Cespedes, E., Dobson, J., Collingwood, J.F., Dobson, Jon, Arenholz, Elke, Telling, N.D., Arenholz, E., Céspedes, Eva, Shelford, Leigh R., Exley, Chris, Exley, C., Jenkins, Catherine A., Everett, J., Shelford, L.R., Telling, Neil D.   +18 more
core   +1 more source

MXene Wrapped Magnetic Mesocrystals for Durable Redox Catalytic Cancer Therapy and Responsive MRI

Advanced Functional Materials, EarlyView.
Conformal wrapping of ultrathin Ti3C2Tx MXene nanosheets on Fe3O4 mesocrystals creates topology‐stabilized Schottky junctions that direct photoinduced electron transfer under NIR irradiation. The unique architecture sustains Fenton catalysis, promotes continuous hydroxyl radical production, and provides photo‐responsive MRI contrast.
Min Jun Ko, Seongchan Kim, Jun‐Hyeok Han, Sanghee Lee, Minji Ahn, Hong En Fu, Young Jun Jang, Yoo Sang Jeon, Weiguo Li, Young Keun Kim, Dong‐Hyun Kim   +10 more
wiley   +1 more source

Iron acquisition strategies in pathogenic fungi

mBio
Iron plays a crucial role in various biological processes, including enzyme function, DNA replication, energy production, oxygen transport, lipid, and carbon metabolism.
Kathryn Takemura, Vanessa Kolasinski, Matteo Del Poeta, Nathalia Fidelis Vieira de Sa, Ashna Garg, Iwao Ojima, Maurizio Del Poeta, Nivea Pereira de Sa   +7 more
doaj   +1 more source

A fungal ABC transporter FgAtm1 regulates iron homeostasis via the transcription factor cascade FgAreA-HapX.

PLoS Pathogens, 2019
Iron homeostasis is important for growth, reproduction and other metabolic processes in all eukaryotes. However, the functions of ATP-binding cassette (ABC) transporters in iron homeostasis are largely unknown.
Zhihui Wang, Tianling Ma, Yunyan Huang, Jing Wang, Yun Chen, H Corby Kistler, Zhonghua Ma, Yanni Yin   +7 more
doaj   +1 more source

Bioinspired Mechanically Robust Organic–Inorganic Hybridized Bio‐Adhesives With up to 50% Inorganic Components by Bi‐Continuous Phase Engineering

Advanced Functional Materials, EarlyView.
A robust plant protein adhesive was prepared by fabricating a bi‐continuous organic–inorganic hybrid structure. Compared with traditional organic–inorganic hybrid adhesives, the addition amount of inorganic phase is increased from 0.2%–3.0% to 50%, and the strength and toughness are increased by 6 and 121 times, respectively.
Zheng Liu, Wenlong Luo, Xu Yang, Xin Zhang, Yuru Zhu, Jingchao Li, Jianzhang Li, Jing Luo, Zhezhe Zhou, Pingan Song, Qiang Gao   +10 more
wiley   +1 more source