Results 181 to 190 of about 178,684 (361)

Talazoparib Formulation Bridging in Cancer Patients—Challenges and the Critical Role of Model‐Informed Drug Development in Approval Despite Failed Bioequivalence

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Talazoparib is a poly(ADP‐ribose) polymerase inhibitor approved for the treatment of breast and prostate cancer. Commercialization of a soft gelatin capsule (SGC) formulation developed post‐approval required a bioequivalence (BE) and food effect (FE) study to bridge SGC with the initial commercial hard capsule (HC) formulation. Study execution
Diane Wang, Cathy Cen Guo, Xizhe Gao, Yibo Wang, Yanke Yu, Anna Plotka, Mohamed Elmeliegy, Haihong Shi, Samantha Johnson, Liza DeAnnuntis, Justin Hoffman   +10 more
wiley   +1 more source

Iron deficiency anemia and the risk of new-onset tinnitus in female patients: a cohort study. [PDF]

Front Nutr
Hung KC, Weng HL, Lai YC, Lin YT, Wu JY, Lin CH, Chen IW.   +6 more
europepmc   +1 more source

Molecularly Engineered Fluorescent Magnetic Microrobots for Sensing High‐Energy Nitroaromatic Explosives in Highly Acidic Aqueous Environments

Small, EarlyView.
Magnetically powered fluorescent microrobots embedded with ketenimine‐based probes enable remote sensing of high‐energy explosive compounds in harsh acidic environments. Upon interaction with picric acid, the fluorescence of the microrobots is quenched, providing a precise “on–off” detection mechanism for selective monitoring in confined and hazardous ...
Nikhil Thekkedath Madhu, N. Senthilnathan, Martin Pumera   +2 more
wiley   +1 more source

The Effect of Iron Deficiency Anemia on the Morphology-Voltage-P Wave Duration (MVP) Risk Score. [PDF]

Ann Noninvasive Electrocardiol
Yildiz G, Yildirim ÖT, Kaya Ş, Ayyildiz FA, Yildiz CG.   +4 more
europepmc   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

Smart Molecules, EarlyView.
Schematic illustration of acute kidney injury and iron metabolism (By Figdraw). Image for iron metabolism, including uptake, storage, utilization, export: Reproduced with permission. Abstract Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates.
Xinyu Tan, Man Li, Jing Chen, Gang Liu, Zhixiang Lu   +4 more
wiley   +1 more source

Economic evaluation of intravenous iron formulations for patients with iron deficiency anemia: a systematic review. [PDF]

Front Health Serv
Xing Z, Mu S, Xue Q, Sun F, Hou G, Zhao Q.   +5 more
europepmc   +1 more source

Challenges in the diagnosis of iron deficiency anemia in aged people

, 2017
Niele Silva de Moraes, Maria Stella Figueiredo   +1 more
openalex   +1 more source

International Practice Variation in Post‐Tonsillectomy Hemorrhage: A Survey Study of Pediatric Otolaryngologists

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background A significant complication of pediatric tonsillectomy is post‐tonsillectomy bleeding (PTB). Management within and outside of the operating room (OR) is not standardized. We consolidated international similarities and differences in PTB management.
Gina M. Spencer, Claire A. Wilson, Jacob Davidson, Julie E. Strychowsky, Claire M. Lawlor, Hannah Burns, Eishaan K. Bhargava, James Fowler, M. Elise Graham   +8 more
wiley   +1 more source

Automated Morphologic Differentiation Between Iron Deficiency Anemia and Thalassemia. [PDF]

J Clin Lab Anal
Guy J, Béné MC, Lopez RS, Maynadié M, Row C.   +4 more
europepmc   +1 more source

Blastocystosis And Iron Deficiency Anemia in Pregnant Women. A Call to Deep in A Little-Known Association

, 2021

openalex   +1 more source