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Mechanisms controlling cellular and systemic iron homeostasis
Nature Reviews Molecular Cell Biology, 2023Bruno Galy +2 more
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2021
Iron deficiency anemia affects approximately one-third of the world's population, and about half the cases are due to iron deficiency. The latest research on iron metabolism published in original articles and systematic reviews is described, and references to recent reviews provided.
Fairweather-Tait, Susan, Sharp, Paul
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Iron deficiency anemia affects approximately one-third of the world's population, and about half the cases are due to iron deficiency. The latest research on iron metabolism published in original articles and systematic reviews is described, and references to recent reviews provided.
Fairweather-Tait, Susan, Sharp, Paul
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Iron and Isoferritins in Iron Overload
Clinical Science, 19821. The ferritin content of iron-overloaded tissues was higher than that of normal tissues. There was also an increased iron content of ferritin extracted from these tissues. 2. In the limited number of tissues that we examined haemosiderin deposition appeared to be greater in the iron-overloaded livers than in the iron-overloaded spleens.
Alice K. Jacobs +2 more
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Iron Deficiency, Iron Overload
Annals of Internal Medicine, 1972Excerpt To the editor: In his recent editorial (1) Dr. V. F. Fairbanks reviewed the tests available for iron deficiency.
J. Sorbie, L. S. Valberg
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Iron deficiency and iron overload
Critical Reviews in Oncology/Hematology, 1985An up to date review of our knowledge of human iron metabolism is given including problems of iron balance, internal transport, and intracellular mechanisms. Current knowledge of the iron proteins is summarized and this background is used in discussing the pathophysiology of iron deficiency and overload, together with the internal derangements such as ...
Allan Jacobs, A.V. Hoffbrand
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Iron Metabolism: Iron Deficiency and Iron Overload
Annual Review of Genomics and Human Genetics, 2000Iron is an essential cofactor in a variety of cellular processes. Except for a few unusual bacterial species, iron is indispensable for living organisms. However, free iron is toxic because of its propensity to induce the formation of dangerous free radicals. Consequently, iron balance is tightly regulated.
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The Effect of Injected Iron on the Absorption of Iron in Iron Deficiency
British Journal of Haematology, 1972Summary. The effects of injected iron on the absorption of iron by iron deficient animals have been studied. When iron deficiency is partly or fully corrected by injection of iron dextran, prolonged and marked depression of iron absorption follows despite the persistence of iron deficiency.
M. John Murray, Nell Stein
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Iron chelators and iron toxicity
Alcohol, 2003Iron chelation may offer new approaches to the treatment and prevention of alcoholic liver disease. With chronic excess, either iron or alcohol alone may individually injure the liver and other organs. In combination, each exaggerates the adverse effects of the other.
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