Results 51 to 60 of about 3,452,077 (357)

Iron-Refractory Iron Deficiency Anemia

open access: yesTurkish Journal of Hematology, 2015
Iron is essential for life because it is indispensable for several biological reactions, such as oxygen transport, DNA synthesis, and cell proliferation. Over the past few years, our understanding of iron metabolism and its regulation has changed dramatically.
Keskin, Ebru Yilmaz, Yenicesu, Idil
openaire   +4 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Small Sample-Oriented Prediction Method of Mechanical Properties for Hot Rolled Strip Steel Based on Model Independent Element Learning

open access: yesIEEE Access
In this paper, a new method based on Model-Agnostic Meta-Learning (MAML) is proposed to address the small sample problem in predicting the mechanical properties of hot rolled strip steel.
Hongyi Wu, Borui Zhang, Zhiwei Li
doaj   +1 more source

Refining mechanism for TiN and solidification structure through a nucleating chain in magnesium-yttrium-treated ultrapure ferritic stainless steel

open access: yesJournal of Materials Research and Technology, 2023
To investigate the refining phenomena of TiN inclusion and macro-/microstructure through heterogeneous nucleation of δ-Fe at TiN encapsulating oxide during solidification in ultrapure ferritic stainless steel, five samples were prepared, denoted as the ...
Xing-Zhi Zhou   +7 more
doaj   +1 more source

Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]

open access: yes, 2017
Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo   +4 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Research on the Jet Characteristics and Dephosphorization Efficiency of Converter Oxygen Lance Blowing CO2-O2 Mixed Gas

open access: yesMetals, 2022
Utilization of CO2 in steelmaking process has attracted extensive attention in recent years, not only because of its social benefits, but also its better metallurgical performance.
Guoli Wei   +6 more
doaj   +1 more source

Photophysiological and photosynthetic complex changes during iron starvation in Synechocystis sp. PCC 6803 and Synechococcus elongatus PCC 7942

open access: yes, 2013
Iron is an essential component in many protein complexes involved in photosynthesis, but environmental iron availability is often low as oxidized forms of iron are insoluble in water.
Bibby, T.S.   +4 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Effect of light on the corrosion behavior of Q450NQR1 weathering steel inthe wet-dry cycle condition

open access: yes工程科学学报, 2016
The effects of no light, half-day light and all-day light on the corrosion behavior of Q450NQR1 weathering steel in the wet-dry cycle condition were examined by corrosion mass loss, scanning electron microscopy, X-ray diffraction and linear polarization ...
HUANG Tao   +4 more
doaj   +1 more source

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