Results 81 to 90 of about 2,029,067 (346)
The Roles of NRF2 in Modulating Cellular Iron Homeostasis
Significance: Iron and oxygen are intimately linked: iron is an essential nutrient utilized as a cofactor in enzymes for oxygen transport, oxidative phosphorylation, and metabolite oxidation.
M. Kerins, Aikseng Ooi
semanticscholar +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Iron-Refractory Iron Deficiency Anemia
Iron is essential for life because it is indispensable for several biological reactions, such as oxygen transport, DNA synthesis, and cell proliferation. Over the past few years, our understanding of iron metabolism and its regulation has changed dramatically.
Keskin, Ebru Yilmaz, Yenicesu, Idil
openaire +4 more sources
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers+3 more
wiley +1 more source
To provide a theoretical basis for the design of super austenitic stainless steel used in flue gas desulfurization environment, by changing the Cu content in 00Cr20Ni18Mo6CuN super austenitic stainless steel to explore the influence of Cu on its ...
Bingbing Li+7 more
doaj
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang+6 more
wiley +1 more source
The status of Chinese permanent magnet industry and R&D activities
It has been 15 years since China dominated the rare earth permanent magnet market in 2001. The annual output of sintered Nd-Fe-B magnets in China reached a new record of 126,300 tonnages in 2015 while the output in 2001 is only 6,500 tonnages.
Shengzhi Dong+3 more
doaj +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang+5 more
wiley +1 more source
Current understanding of iron homeostasis.
Iron is an essential trace element, but it is also toxic in excess, and thus mammals have developed elegant mechanisms for keeping both cellular and whole-body iron concentrations within the optimal physiologic range.
G. Anderson, D. Frazer
semanticscholar +1 more source