Results 51 to 60 of about 6,230,717 (227)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Brooches in Iron Age and Roman Britain Database

open access: yes, 2023
This collection comprises a database and related documents containing details of all Iron Age and Roman brooches analysed by the late Don Mackreth and synthesised in his seminal work, Brooches in Iron age and Roman Britain, published in 2011 by Oxbow ...
Donald Mackreth
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Late Iron Age longhouse chronology

open access: yesDanish Journal of Archaeology, 2017
This paper presents a formalised chronological study of the longhouses of the Late Iron Age. This is based on the correspondence analysis of data relating to house ground plans recorded at a number of Iron Age settlements in central and eastern Jutland,
Stine Vestergaard Laursen   +1 more
doaj   +1 more source

The Emergence of Inland Settlement in Northern Dobruja at the End of the Archaic Period. A Newly Surveyed Settlement on Celic Dere Valley [PDF]

open access: yesPeuce, 2021
In addition to the decades-long known archaeological ensemble (consisting of a 6th-3rd centuries BC settlement and tumuli necropolis) on Celic Dere valley, in Northern Dobruja, a second settlement (Cassiana) of the same period was recently documented ...
Maria-Magdalena ȘTEFAN   +4 more
doaj  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

The Iron Age

open access: yes, 2003
Made available here with permission from the copyright holder: Cambridge University Press.
openaire   +2 more sources

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

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