Results 101 to 110 of about 96,366 (224)

Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage‐Myofibroblast Transition

Advanced Science, EarlyView.
Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang, Guan‐Lin Guo, Xiao‐Hui Guan, Min Hu, Qi‐Ming Huang, Ding‐Wen Guo, Hao‐Cheng Gu, You‐Qiong Zhuo, Ning Li, Hong‐Bo Xin, Ke‐Yu Deng   +10 more
wiley   +1 more source

Biointegrated Multilayer Stretchable OLED Platform With Strain‐Decoupled Architecture for Durable Phototherapeutic Applications

Advanced Science, EarlyView.
A multilayer stretchable organic light‐emitting diode (SOLED) patch enables conformal, high‐fill‐factor phototherapeutic illumination through vertically decoupled electrodes and robust encapsulation. The textile‐based SOLED platform delivers stable skin‐contact red light for wearable phototherapy and 5‐aminolevulinic acid (ALA)‐mediated photodynamic ...
Young Hyun Son, Myeongheon Lee, Jun‐Yeop Song, Hyo‐Jung Kwon, Kyung Cheol Choi, Jeong Hyun Kwon   +5 more
wiley   +1 more source

Une pale de roue à eau à deux jantes d’époque romaine découverte à Sorigny (Indre-et-Loire)

Revue Archéologique du Centre de la France, 2017
The archaeological rescue excavation carried out at “la Pièce des Viviers” (Sorigny, Indre-et-Loire) has revealed a succession of rural settlements from the second Iron Age and Roman Antiquity.
Florian Sarreste
doaj  

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

Advanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Lintao Luo, Jie Zhong, Zhaxylyk Sabitov, CAGDP Consortium†, Lan‐Hai Wei, Chao Liu, Maxat Zhabagin, Guanglin He   +11 more
wiley   +1 more source

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

Mapping Steroidogenic Perturbations Under Endocrine Disruptor Mixtures Across Demographic Subgroups: Structural and Metabolomic Insights

Advanced Science, EarlyView.
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen, Lei Huang, Yingtong Jiang, Guohong Zhao, Mengyuan Zhu, Xiulian Lu, Lang Lang, Akinpelumi Oluwatobiloba Esther, Longhao Fan, Yuqi Jiang, Chang Sun, Xiaoling Zhang, Kun Zhou, Xiaoming Ji, Minjian Chen   +14 more
wiley   +1 more source

A Multimodal Haptic Feedback Interface with Thin‐Film Compliant Mechanism

Advanced Science, EarlyView.
Multimodal haptic devices can trigger different mechanoreceptors, enabling richer haptic information. This study presents an electromagnetic multimodal haptic device capable of delivering indentation, stretch, and vibration stimuli. The device is enabled by a novel polymer thin‐film compliant mechanism that provides high translational compliance along ...
Jingjing Wan, Emanuele Nicotra, James Davies, Kefan Zhu, Quang Anh Nguyen, Sinuo Zhao, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Hermione Truong, Patrick Pruscino, Tan Huynh, Phuoc Thien Phan, Hoang‐Phuong Phan, Nigel Hamilton Lovell, Thanh Nho Do   +15 more
wiley   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

The genetic landscape of northeastern Iberian communities from the early to late Iron Age. [PDF]

iScience
Cuesta-Aguirre DR, Roca-Rada X, Di Biase B, Vinueza-Espinosa DC, Sandoval-Ávila C, Ravishankar S, Molist Capella N, Duran I Caixal M, Mestres Santacreu I, Junyent E, Alonso N, Martinez Majoral J, Knudsen AK, Lanigan LT, Schroeder H, Llamas B, Malgosa A, Santos C.   +17 more
europepmc   +1 more source

Engineering Strategies to Suppress Thermal Runaway Propagation in Lithium‐Ion Battery: Mechanisms, Metrics, Materials, and Evaluation Methods

Advanced Science, EarlyView.
Thermal runaway propagation can transform a single‐cell failure into a system‐level hazard in lithium‐ion battery packs. This review clarifies how heat transfer, gas venting, combustion, and configuration govern cell‐to‐cell failure, and links measurable metrics, pathway‐oriented suppression materials, and experimental/modeling tools to guide safer ...
Jinrong Su, Anna DiFelice, Jayani Mawela, Jianing Gan, Shuai Che, Wonhee Cho, Hanghang Yan, Yaohong Xiao, Xinxin Yao, Xiangwei Guo, Rui Wang, Dingchuan Xue, Hanlong Liu, Solomon Adera, Zhan Chen, Lei Chen   +15 more
wiley   +1 more source