Results 71 to 80 of about 16,395,144 (252)

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang   +9 more
wiley   +1 more source

The Mun Valley and Central Thailand in prehistory: integrating two cultural sequences

open access: yesOpen Archaeology, 2014
This paper compares the later prehistory in two regions of Thailand. The Mun Valley lies on the eastern side of the Phetchabun Range, the Lopburi Region (LR) to the west. They are linked by a major pass.
Higham Charles Franklin   +1 more
doaj   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

Cultural Encounters in Iron Age Europe [PDF]

open access: yes, 2016
NoCultural encounters form a dominant theme in the study of Iron Age Europe. This was particularly acute in regions where urbanising Mediterranean civilisations came into contact with ‘barbarian’ worlds.
Armit, Ian   +4 more
core   +3 more sources

Iron Deficiency Anaemia and Beta Thalassaemia Trait in Anaemic Pregnant Women.

open access: yesمجلة كلية الطب, 2010
Back ground: Anaemia is one of commonest health problems in antenatal care units of developing countries and contributes significantly to increased maternal and fetal morbidity and mortality.
Haider H. AL – Shammari
doaj   +1 more source

Brooches in Iron Age and Roman Britain Database

open access: yes, 2023
This collection comprises a database and related documents containing details of all Iron Age and Roman brooches analysed by the late Don Mackreth and synthesised in his seminal work, Brooches in Iron age and Roman Britain, published in 2011 by Oxbow ...
Donald Mackreth
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Elementi decorativi nella ceramica della seconda età del Ferro a sud del Po [PDF]

open access: yesStudia Hercynia
Decoration Features of Second Iron Age Pottery South of the Po The paper analyses on a chronological typological level the decorative syntax present on impasto pottery from the Late Iron Age (Ligure III period: 475–89 BC) in lower Piedmont (inner ...
Marina Giaretti, Marica Venturino
doaj  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

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