Results 81 to 90 of about 1,120,250 (298)

Impact of Hemoglobin and Iron Deficiency on Mortality in Patients with Acute Myocardial Infarction in Intensive Care Units: A Retrospective Study from MIMIC-IV

Reviews in Cardiovascular Medicine
Background: Anemia and iron deficiency (ID) are common in patients with acute myocardial infarction (AMI), especially those in intensive care units (ICU).
Fangyuan Luo, Zhe Wang, Tong Gao, Baofu Wang, Yijie Gao, Mengru Liu, Hong Jiang, Xianlun Li   +7 more
doaj   +1 more source

Hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with macrocytosis

Journal of the Formosan Medical Association, 2019
Background/Purpose: Macrocytosis is defined as having the mean corpuscular volume (MCV) ≧ 100 fL. This study evaluated whether 41 atrophic glossitis (AG) patients with macrocytosis had significantly higher frequencies of anemia, hematinic deficiencies ...
Chun-Pin Chiang, Yu-Hsueh Wu, Julia Yu-Fong Chang, Yi-Ping Wang, Yang-Che Wu, Andy Sun   +5 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Potential Impacts of Iron Biofortification in India [PDF]

Iron deficiency is a widespread nutritional problem in developing countries, causing impaired physical activity and cognitive development, as well as maternal mortality.
Sachdev, H.P.S., Qaim, Matin, Stein, Alexander J., Meenakshi, J.V., Nestel, Penelope, Bhutta, Zulfiqar A.   +5 more
core  

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Impact of oil fortification with iron in the prevention of anemia—A systematic review

Journal of Education and Health Promotion
Micronutrient malnutrition has gained its significant influence on public health and a role in the worldwide disease burden in recent years. Through fortification, the nutritional profile of staple foods is enhanced, making them more nutritious and ...
Ramesh Holla, Bhaskaran Unnikrishnan, Mithun Rao, Vani Verma, Chanchal Chaudhary, Vasudeva Guddattu, Jobinse Jose, Nisha Abdul Khader, Apoorva M. Shankaranarayana, Arunima Biswas   +9 more
doaj   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Genetically Modifying Rice to Fight Iron Deficiencies

, 2019
In an effort to eliminate or lessen the effects of iron deficiencies, there will be research on genetic modification of rice to contain a greater amount of iron that the human body can actively absorb.
Faris, Rachel
core  

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source