Results 81 to 90 of about 2,170,501 (423)

Iron refractory iron deficiency anemia [PDF]

open access: yesHaematologica, 2013
Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6 gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an essential role in down-regulating hepcidin, the key regulator of iron homeostasis.
De Falco, Luigia   +8 more
openaire   +6 more sources

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

The usefulness of soluble transferrin receptor (sTfR) in differentiating anemia occurring in young children [PDF]

open access: yes, 2012
We evaluated the usefulness of soluble transferrin receptor (sTfR) and of the sTfR/log ferritin index(sTfR/logF) in the differentiation of anemia in young children.
Dółka, Elżbieta   +3 more
core   +2 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Prevalence of iron deficiency among patients with chronic heart failure attending Rizgary and Hawler teaching hospitals in Erbil City

open access: yesZanco Journal of Medical Sciences, 2018
Background and objectives: Iron deficiency is an emerging problem in patients with chronic heart failure and could be a potential therapeutic target. This study aimed to determine the prevalence, severity, and type of iron deficiency among patients with ...
Hawree Ibrahim Othman   +1 more
doaj   +1 more source

Iron Deficiency Anaemia [PDF]

open access: yes, 2017
Iron deficiency anaemia as the most common nutrition disorder has only marginal reduction globally during recent decades, with the highest burden in pregnant women and young children.
Li, Chao   +3 more
core   +1 more source

International consensus statement on the peri‐operative management of anaemia and iron deficiency

open access: yesAnaesthesia, 2017
Despite current recommendations on the management of pre‐operative anaemia, there is no pragmatic guidance for the diagnosis and management of anaemia and iron deficiency in surgical patients.
M. Muñoz   +14 more
semanticscholar   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Iron abundance in the prototype PG1159 star, GW Vir pulsator PG1159-035, and related objects [PDF]

open access: yes, 2011
We performed an iron abundance determination of the hot, hydrogen deficient post-AGB star PG1159-035, which is the prototype of the PG1159 spectral class and the GW Vir pulsators, and of two related objects (PG1520+525, PG1144+005), based on the first detection of Fe VIII lines in stellar photospheres.
arxiv   +1 more source

The Stoichiometry of FeSe [PDF]

open access: yesSol. St. Comm. 149, 1507-1509 2009, 2009
Tetragonal iron selenide, FeSe, the layered parent compound of the recently discovered superconducting arsenide family, has previously been shown to be non magnetic and superconducting with a critical temperature near 8 K. There has, however, been a lack of consensus as to whether selenium vacancies present due to large deviations from ideal ...
arxiv   +1 more source

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