Results 51 to 60 of about 132,681 (305)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Iron-Deficiency Anemia in CKD: A Narrative Review for the Kidney Care Team

Kidney Medicine, 2023
Anemia is a common complication of chronic kidney disease (CKD) and is associated with increased mortality and reduced health-related quality of life.
Debra Hain, Donna Bednarski, Molly Cahill, Amy Dix, Bryce Foote, Mary S. Haras, Rory Pace, Orlando M. Gutiérrez   +7 more
doaj   +1 more source

Effects of Daily Zinc, Daily Multiple Micronutrient Powder, or Therapeutic Zinc Supplementation for Diarrhea Prevention on Physical Growth, Anemia, and Micronutrient Status in Rural Laotian Children: A Randomized Controlled Trial. [PDF]

, 2019
ObjectivesTo evaluate the optimal zinc supplementation strategy for improving growth and hematologic and micronutrient status in young Laotian children.Study designIn total, 3407 children aged 6-23 months were randomized to receive either daily ...
Arnold, Charles D, Barffour, Maxwell A, Bounheuang, Bangone, Brown, Kenneth H, Chanhthavong, Bigphone, Hess, Sonja Y, Hinnouho, Guy-Marino, Kounnavong, Sengchanh, Ratsavong, Kethmany, Sengnam, Khanpaseuth, Sitthideth, Dalaphone, Wessells, K Ryan   +11 more
core  

Low Dose Daily Iron Supplementation Improves Iron Status and Appetite but not Anemia, Whereas Quarterly Anthelminthic Treatment Improves Growth, Appetite and Anemia in Zanzibari Preschool Children. [PDF]

, 2004
Iron deficiency and helminth infections are two common conditions of children in developing countries. The consequences of helminth infection in young children are not well described, and the efficacy of low dose iron supplementation is not well ...
Adam, Albonico, Albonico, Antonio Montresor, Brown, Caulfield, Crompton, Davis, de Andraca, Dickson, Diggle, Donnen, Freij, Greenberg, Gupta, Gupta, Hababu M. Chway, Idjradinata, James M. Tielsch, Jape Khatib Jape, Jelkmann, Kloetzel, Lackritz, Langhans, Levin, Lorenzo Savioli, Lozoff, Marco Albonico, Menendez, Montresor, National Research Council, Nelson, Pelletier, Pinero, Plata-Salaman, Rebecca J. Stoltzfus, Reeds, Rosenberg, Rousham, Savioli, Schultz, Smith, Solomons, Stoltzfus, Stoltzfus, Stoltzfus, Stoltzfus, Thein-Hlaing, Trape, Verhoef, Warren, Willett, World Health Organization, World Health Organization Expert Committee   +53 more
core   +1 more source

AML‐Targeted Metal‐Polyphenol Nanoplatform Induces Ferroptosis‐ICD Cascade for Antitumor Immunity Boosting

Advanced Science, EarlyView.
Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang, Jingxuan Wang, Kerong Tu, Xiaobing Huang, Liangliang Lv, Mingjie Peng, Qiqi Xu, Hongmei Liu, Qiang Sun, Lulu Cai   +9 more
wiley   +1 more source

Evaluation of oxidative status in iron deficiency anemia through total antioxidant capacity measured using an automated method

Turkish Journal of Hematology, 2011
OBJECTIVE: Oxidative stress, an increase in oxidants and/or a decrease in antioxidant capacity, is one of the potential biochemical mechanisms involved in the pathogenesis of iron deficiency anemia.
Mehmet Aslan, Mehmet Horoz, Hakim Çelik
doaj   +3 more sources

DIAGNOSIS LABORATORIK ANEMIA DEFISIENSI BESI

e-Jurnal Medika Udayana, 2014
Iron deficiency anemia is a decreament of iron level in the body. Iron deficiency anemiais oftenly seen, especially in the tropical countries or the third world country thatassociated with social economic rate. Iron deficiency anemia happens in more than
Dina Sophia Margina, Sianny Herawati, I W P Sutirta Yasa   +2 more
doaj  

Pathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivo

Haematologica, 2011
Background Increased levels of hepcidin, the master regulator of iron homeostasis, contribute to the diversion of iron underlying the anemia of chronic disease.
Igor Theurl, Andrea Schroll, Manfred Nairz, Markus Seifert, Milan Theurl, Thomas Sonnweber, Hasan Kulaksiz, Guenter Weiss   +7 more
doaj   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source