The Pharmacokinetics and Pharmacodynamics of Iron Preparations [PDF]
Pharmaceutics, 2011 Standard approaches are not appropriate when assessing pharmacokinetics of iron supplements due to the ubiquity of endogenous iron, its compartmentalized sites of action, and the complexity of the iron metabolism.
Susanna Burckhardt, Peter Geisser
doaj +7 more sources
Hypersensitivity to Intravenous Iron Preparations [PDF]
Children, 2022 Intravenous iron is widely used for the treatment of iron deficiency anemia when adherence to oral iron replacement is poor. Acute hypersensitivity reactions during iron infusions are very rare but can be life threatening.
Silvia Caimmi +12 more
doaj +7 more sources
The role of DSM 17938 for the absorption of iron preparations in children with iron deficiency anemia [PDF]
Korean Journal of Pediatrics, 2019 Purpose To determine whether Lactobacillus reuteri DSM 17938 plays a role in absorption of iron preparations given to children with iron deficiency anemia (IDA).
Jeanette Manoppo +4 more
doaj +4 more sources
Use of Different Iron Preparations for Prophylaxis and Effects on Iron Status in Infancy. [PDF]
Healthcare (Basel)Aim: To evaluate using different iron preparations for iron deficiency and/or iron deficiency anemia prophylaxis in infants and their iron status. Methods: In this study, we retrospectively evaluated the electronic patient records of 651 healthy children
Tosyalı M +5 more
europepmc +4 more sources
Intravenous iron preparations transiently generate non-transferrin-bound iron from two proposed pathways [PDF]
Haematologica, 2020 Intravenous iron-carbohydrate complex preparations (IVIP) are noninterchangeable pro-drugs: their pharmacokinetics (PK) varies determined by semi-crystalline iron core and carbohydrate shell structures, influences pharmacodynamics (PD) and thus efficacy
Maciej W. Garbowski +5 more
doaj +3 more sources
Impact of nausea/vomiting on EQ-5D-5L utility scores in patients taking iron preparations for heavy menstrual bleeding or anemia. [PDF]
BMC Womens Health, 2023 Background The purpose of this study was to establish an estimating equation to predict the 5-level EQ-5D version (EQ-5D-5L) utility score in patients taking iron preparations for heavy menstrual bleeding (HMB) or anemia and to evaluate whether the ...
Ito K, Mitobe Y, Inoue R, Momoeda M.
europepmc +2 more sources
Iron preparations for women of reproductive age with iron deficiency anaemia in pregnancy (FRIDA): a systematic review and network meta-analysis. [PDF]
Lancet Haematol, 2021 Background Numerous iron preparations are available for the treatment of iron deficiency anaemia in pregnancy. We aimed to provide a summary of the effectiveness and safety of iron preparations used in this setting. Methods We did a systematic review and
Rogozińska E +10 more
europepmc +2 more sources
Iron Therapy in Patients with Heart Failure and Iron Deficiency: Review of Iron Preparations for Practitioners. [PDF]
Am J Cardiovasc Drugs, 2017 In patients with heart failure (HF), iron deficiency (ID) correlates with decreased exercise capacity and poor health-related quality of life, and predicts worse outcomes. Both absolute (depleted iron stores) and functional (where iron is unavailable for
Drozd M +3 more
europepmc +2 more sources
Assessment of Dextran Antigenicity of Intravenous Iron Preparations with Enzyme-Linked Immunosorbent Assay (ELISA). [PDF]
Int J Mol Sci, 2016 Intravenous iron preparations are typically classified as non-dextran-based or dextran/dextran-based complexes. The carbohydrate shell for each of these preparations is unique and is key in determining the various physicochemical properties, the ...
Neiser S +4 more
europepmc +2 more sources
Impact of individual intravenous iron preparations on the differentiation of monocytes towards macrophages and dendritic cells. [PDF]
Nephrol Dial Transplant, 2016 Background Treatment of iron deficiency with intravenous (i.v.) iron is a first-line strategy to improve anaemia of chronic kidney disease. Previous in vitro experiments demonstrated that different i.v.
Fell LH +8 more
europepmc +2 more sources