Results 111 to 120 of about 1,224,659 (295)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Study and optimization of ion-irradiated High-Tc Josephson nanoJunctions by Monte Carlo simulations

open access: yes, 2007
High Tc Josephson nanoJunctions (HTc JnJ) made by ion irradiation have remarkable properties for technological applications. However, the spread in their electrical characteristics increases with the ion dose. We present a simple model to explain the JnJ
Bergeal, N.   +7 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Cancer classification with radiomics in controlled preclinical models

open access: yesScientific Reports
The premise of radiomics involves extracting high-dimensional quantitative features from medical images to aid clinical decision-making. While radiomics has shown promise in predicting disease characteristics, concerns regarding confounders ...
Kyle Drover   +9 more
doaj   +1 more source

Irradiation-induced Ag nanocluster nucleation in silicate glasses: analogy with photography

open access: yes, 2007
The synthesis of Ag nanoclusters in sodalime silicate glasses and silica was studied by optical absorption (OA) and electron spin resonance (ESR) experiments under both low (gamma-ray) and high (MeV ion) deposited energy density irradiation conditions ...
A. A. Ahmed   +33 more
core   +3 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Powder metallurgy processed metal-matrix friction materials for space applications

open access: yesFriction, 2017
Owing to the increasing demand for tribological brakes for space applications, the development of novel materials and advanced technologies is necessary.
Yelong Xiao   +5 more
doaj   +1 more source

Wind inhibition by X-ray irradiation in HMXBs: the influence of clumping and the final X-ray luminosity

open access: yes, 2018
In wind-powered X-ray binaries, the radiatively driven stellar wind from the primary may be inhibited by the X-ray irradiation. This creates the feedback that limits the X-ray luminosity of the compact secondary.
Krticka, Jiri   +2 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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