Results 111 to 120 of about 1,224,659 (295)
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Study and optimization of ion-irradiated High-Tc Josephson nanoJunctions by Monte Carlo simulations
High Tc Josephson nanoJunctions (HTc JnJ) made by ion irradiation have remarkable properties for technological applications. However, the spread in their electrical characteristics increases with the ion dose. We present a simple model to explain the JnJ
Bergeal, N. +7 more
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Cancer classification with radiomics in controlled preclinical models
The premise of radiomics involves extracting high-dimensional quantitative features from medical images to aid clinical decision-making. While radiomics has shown promise in predicting disease characteristics, concerns regarding confounders ...
Kyle Drover +9 more
doaj +1 more source
Irradiation-induced Ag nanocluster nucleation in silicate glasses: analogy with photography
The synthesis of Ag nanoclusters in sodalime silicate glasses and silica was studied by optical absorption (OA) and electron spin resonance (ESR) experiments under both low (gamma-ray) and high (MeV ion) deposited energy density irradiation conditions ...
A. A. Ahmed +33 more
core +3 more sources
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Powder metallurgy processed metal-matrix friction materials for space applications
Owing to the increasing demand for tribological brakes for space applications, the development of novel materials and advanced technologies is necessary.
Yelong Xiao +5 more
doaj +1 more source
In wind-powered X-ray binaries, the radiatively driven stellar wind from the primary may be inhibited by the X-ray irradiation. This creates the feedback that limits the X-ray luminosity of the compact secondary.
Krticka, Jiri +2 more
core +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source

