Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman+4 more
wiley +1 more source
New Mechanisms of Formation of Irritable Bowel Syndrome in Children [PDF]
The review article is devoted to the analysis of foreign and domestic studies on irritable bowel syndrome in children. The author considers neuro-immuno-endocrine mechanisms of functional pathology formation, studies new pathogenetic mechanisms ...
Halimovna , Rasulova Saodat
core +2 more sources
The irritable bowel syndrome [PDF]
Summary Irritable bowel syndrome is a common disorder varying in severity from trivial to incapacitating. The pathophysiology and epidemiology are gradually being unravelled and it is now becoming apparent just how poor the quality of life of some of these patients can be. It is no longer acceptable practice to diagnose the condition and
Francis, C Y, Whorwell, P J
openaire +4 more sources
Lower gastrointestinal function after surgery for deep endometriosis: A prospective cohort study
Abstract Objective To prospectively compare long‐term lower gastrointestinal function before and after laparoscopic surgery for deep endometriosis (DE). Methods In this prospective observational study we followed 149 patients with confirmed DE who were treated surgically.
Uri P. Dior+6 more
wiley +1 more source
Gut microbiota‐stem cell niche crosstalk: A new territory for maintaining intestinal homeostasis
Intestinal stem cells (ISCs) are protected by their niche and are regulated by Wnt, bone morphogenetic protein, and Notch. ISCs and their relationship with intestinal microbiota provide a feasible pathway to alleviate intestinal diseases. Diverse bacteria‐related postbiotics regulate ISCs and maintain their homeostasis.
Ning Ma+3 more
wiley +1 more source
Neonatal Bowel Sound Detection Using Convolutional Neural Network and Laplace Hidden Semi-Markov Model [PDF]
Abdominal auscultation is a convenient, safe and inexpensive method to assess bowel conditions, which is essential in neonatal care. It helps early detection of neonatal bowel dysfunctions and allows timely intervention. This paper presents a neonatal bowel sound detection method to assist the auscultation. Specifically, a Convolutional Neural Network (
arxiv +1 more source
TransCon PTH is an investigational once‐daily prodrug providing sustained release of active PTH designed to maintain stable PTH levels in the physiological range for 24 hours/day. The PaTHway trial met all primary and key secondary endpoints with statistically significant differences from placebo. Most adverse events (AEs) were mild/moderate. Injection‐
Aliya A Khan+19 more
wiley +1 more source
Irritable bowel syndrome and active inflammatory bowel disease diagnosed by faecal gas analysis [PDF]
© 2016 John Wiley & Sons Ltd Background: Inflammatory bowel disease and irritable bowel syndrome may present in a similar manner. Measuring faecal calprotectin concentration is often recommended to rule out inflammatory bowel disease, however, there ...
Aggio+29 more
core +1 more source
Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal [PDF]
Irritable bowel syndrome is a group of functional gastrointestinal disorders with not yet fully clarified etiology. Recent evidence suggesting that mast cells may play a central role in the pathogenesis of irritable bowel syndrome paves the way for ...
Fabisiak, Adam+4 more
core +1 more source
The Role of Personality Traits in Predicting Irritable Bowel Syndrome Mediated by Anxiety Sensitivity [PDF]
Introduction: The significance of psychological and personality factors in predicting and treating irritable bowel syndrome has garnered special attention from researchers and therapists in recent years. The aim of this study was to examine the influence
Ezzatollah Ahmadi+2 more
doaj +1 more source