Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis [PDF]
Clinical and Translational Allergy, 2021 Background The pathogenesis of contact dermatitis, a common inflammatory skin disease with limited treatment options, is held to be driven by inflammasome activation induced by allergens and irritants.
Hanna Bonnekoh +13 more
doaj +7 more sources
European Surveillance System on Contact Allergies (ESSCA): Characteristics of patients patch tested and diagnosed with irritant contact dermatitis [PDF]
Contact Dermatitis, 2021 Background Irritant contact dermatitis (ICD) is caused by the acute locally toxic effect of a strong irritant, or the cumulative exposure to various weaker physical and/or chemical irritants.
L. Loman +29 more
semanticscholar +8 more sources
Development of Guar Gum Hydrogel Containing Sesamol-Loaded Nanocapsules Designed for Irritant Contact Dermatitis Treatment Induced by Croton Oil Application [PDF]
Pharmaceutics, 2023 Irritant contact dermatitis is usually treated with corticosteroids, which cause expressive adverse effects. Sesamol is a phenolic compound with anti-inflammatory and antioxidant properties.
Vinicius Costa Prado +5 more
doaj +3 more sources
Cytokines and Chemokines in Irritant Contact Dermatitis [PDF]
Mediators of Inflammation, 2013 Irritant contact dermatitis is a result of activated innate immune response to various external stimuli and consists of complex interplay which involves skin barrier disruption, cellular changes, and release of proinflammatory mediators.
Haur Yueh Lee +3 more
doaj +3 more sources
Irritant Contact Dermatitis — a Review [PDF]
Curr Dermatol Rep, 2022 Irritant contact dermatitis is the most common form of contact dermatitis and the most common occupational skin disease. This review provides a comprehensive summary of the endogenous and exogenous factors that play a role in the pathogenesis of irritant
Kajal Patel, R. Nixon
semanticscholar +2 more sources
Causes of irritant contact dermatitis after occupational skin exposure: a systematic review [PDF]
Int Arch Occup Environ Health, 2021 Purpose Irritant contact dermatitis (ICD) is a major cause of occupational disease. The aim was to review the relation between exposure to occupational irritants and ICD and the prognosis of ICD.
G. Jacobsen +5 more
semanticscholar +2 more sources
Irritant contact dermatitis in healthcare workers as a result of the COVID‐19 pandemic: a cross‐sectional study [PDF]
Clin Exp Dermatol, 2020 COVID‐19 healthcare workers (HCWs) require frequent handwashing and use of personal protective equipment (PPE) to prevent infection. However, evidence is emerging that these practices are causing adverse effects on their skin integrity.
L. Kiely +6 more
semanticscholar +2 more sources
Frequent handwashing amidst the COVID‐19 outbreak: prevention of hand irritant contact dermatitis and other considerations [PDF]
Health Sci Rep, 2020 Coronavirus disease 2019 (COVID-19) primarily spreads via respiratory droplets, but it can also spread via contact with contaminated surfaces or objects.
B. Abtahi-Naeini
semanticscholar +2 more sources
Machine-learning–driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis [PDF]
Proc Natl Acad Sci U S A, 2020 Significance Contact dermatitis is an inflammatory skin disorder that arises from direct skin contact with irritants or allergens. Representing over 90% of occupational skin disorders, it has a considerable socioeconomic impact, and patients suffering ...
Vittorio Fortino +15 more
semanticscholar +3 more sources
Irritant contact dermatitis due to povidone-iodine following a surgical intervention: An unusual case report [PDF]
SAGE Open Medical Case Reports, 2023 The most common day-to-day antiseptic preparation used before any surgery usually involves povidone-iodine. Any irritant reaction to it can be devastating for the patient’s aspect and would raise the need for a preliminary investigation prior to going ...
Mohammed Affan Osman Khan +4 more
doaj +2 more sources