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Requirements for Alternative In Vitro and In Silico Skin Models of Irritant and Allergic Contact Dermatitis. [PDF]

open access: yesContact Dermatitis
Portugal-Cohen M   +9 more
europepmc   +1 more source

Irritant Contact Dermatitis

Reviews on Environmental Health, 2014
Filaggrin may modify the risk for irritant contact dermatitis (ICD) in different ways. In the stratum corneum (SC), which is the principal barrier of the skin, filaggrin is responsible for the structural strength by aggregating the keratin filaments, while its breakdown products contribute to adequate hydration, pH balance, and anti-bacterial defence ...
Kezić, S., Visser, Maaike J.
  +7 more sources

Irritant Contact Dermatitis

Clinical Reviews in Allergy & Immunology, 2018
Contact dermatitis accounts for 95% of occupational skin disorders. Irritant contact dermatitis (ICD) is often caused by cumulative exposure to weak irritants, accounting for 80% of all cases of contact dermatitis. ICD can co-exist with atopic dermatitis (AD) and allergic contact dermatitis (ACD).
Sonia N. Bains   +2 more
  +5 more sources

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