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Cytokines and irritant contact dermatitis
Toxicology Letters, 1998Skin irritation is a complex phenomenon that involves resident epidermal cells, fibroblasts of dermis, and endothelial cells as well as invading leukocytes interacting with each other under the control of a network of cytokines and lipid mediators. Keratinocytes play an important role in the initiation and perpetuation of skin inflammatory reactions ...
E. Corsini, C.L. Galli
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2021
Irritant contact dermatitis is a non immunological local inflammatory skin reaction to external agents. The related skin damage can be the result of acute toxic aggression, generally linked to a single strong etiological agent, or of repeated cumulative aggression by several weaker irritants.
Caterina Foti +3 more
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Irritant contact dermatitis is a non immunological local inflammatory skin reaction to external agents. The related skin damage can be the result of acute toxic aggression, generally linked to a single strong etiological agent, or of repeated cumulative aggression by several weaker irritants.
Caterina Foti +3 more
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Irritant Dermatitis in the Workplace
Dermatologic Clinics, 1994Irritant contact dermatitis is the most frequent occupational skin disease resulting in considerable morbidity and economic losses to workers, employers, and insurers. This article reviews pathogenesis, epidemiology, diagnosis, and treatment of irritant dermatitis at the workplace and stresses the importance of integrated preventive measures that must ...
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2010
Publisher Summary This chapter discusses the factors influencing irritant potential, delineates general clinical presentations of irritant dermatitis, and addresses workup and treatment. In addition, it addresses methods of evaluating a chemical's irritant potential and discusses the irritation potential of some agricultural chemicals and plants ...
Howard I. Maibach +2 more
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Publisher Summary This chapter discusses the factors influencing irritant potential, delineates general clinical presentations of irritant dermatitis, and addresses workup and treatment. In addition, it addresses methods of evaluating a chemical's irritant potential and discusses the irritation potential of some agricultural chemicals and plants ...
Howard I. Maibach +2 more
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Contact Irritant Dermatitis in Kenya
Journal of the Royal Army Medical Corps, 2012Kenya is one of the British Army’s main training areas outside of the UK and the flora and fauna present the physicians with several challenges. A 22 year old infantry soldier presented with a vesicular, linear painful rash across his chest caused by the chemical excreted from the Staphylinid or rove beetle, known locally as the Nairobi fly.
Toby Nelson, S Raitt
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Oxidative stress in allergic and irritant dermatitis: from basic research to clinical management.
Recent Patents on Inflammation & Allergy Drug Discovery, 2012Allergic and irritant skin diseases may be the results of representative inflammatory response in the skin. It has been established that inflammatory response includes reactive oxygen species, reactive nitrogen species, and free radicals.
K. Nakai, K. Yoneda, Y. Kubota
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Dermatitis caused by physical irritants
British Journal of Dermatology, 2002Although physical irritant contact dermatitis (PICD) is a common occupational dermatosis, it is one of the least well understood because of its multiple types, lack of diagnostic test, and the many mechanisms involved in its production.To characterize the materials and mechanisms of physical irritation of the skin.We did a retrospective analysis over ...
Morris-Jones, R +5 more
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Archives of Dermatology, 1990
In the field of contact dermatitis, a number of excellent references are available to guide the practicing clinician, in addition to Alexander Fisher's classic text, Contact Dermatitis . One area that has not been specifically covered is that of irritant contact dermatitis. For this reason, the editors, Edward M.
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In the field of contact dermatitis, a number of excellent references are available to guide the practicing clinician, in addition to Alexander Fisher's classic text, Contact Dermatitis . One area that has not been specifically covered is that of irritant contact dermatitis. For this reason, the editors, Edward M.
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Allergic and irritant contact dermatitis
European Journal of Dermatology, 2009Irritant and allergic contact dermatitis are common inflammatory skin diseases induced by repeated skin contact with low molecular weight chemicals, called xenobiotics or haptens. Although both diseases may have similar clinical presentations, they can be differentiated on pathophysiological grounds.
Anca Hennino +4 more
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Dermatologic Clinics, 1984
The variability of irritant reactions requires that irritants be thought of as having a range of concentrations that produce reactions. The concept of an ID50 helps to keep some of these variables in mind. Individuals may have altered irritant thresholds because of eczematous dermatitis elsewhere, strongly positive patch tests, and factors that enhance
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The variability of irritant reactions requires that irritants be thought of as having a range of concentrations that produce reactions. The concept of an ID50 helps to keep some of these variables in mind. Individuals may have altered irritant thresholds because of eczematous dermatitis elsewhere, strongly positive patch tests, and factors that enhance
openaire +2 more sources