Results 41 to 50 of about 94,130 (384)

Expression of taste receptors in Solitary Chemosensory Cells of rodent airways

open access: yesBMC Pulmonary Medicine, 2011
Background Chemical irritation of airway mucosa elicits a variety of reflex responses such as coughing, apnea, and laryngeal closure. Inhaled irritants can activate either chemosensitive free nerve endings, laryngeal taste buds or solitary chemosensory ...
Sbarbati Andrea   +3 more
doaj   +1 more source

Irritants, Irritancy and Irritant Induced Asthma

open access: yesJournal of Allergy & Therapy, 2018
An irritant represents a non-corrosive chemical that causes a reversible non-immunologic inflammatory reaction after direct contact with the skin, eyes, nose and/or respiratory system. There are numerous reactions to irritants including change in spirometry, elevated exhaled breath levels of nitric oxide, enhancement of the response to allergen ...
openaire   +1 more source

Preclinical Ophthalmotoxicity Studies of Medicinal Products: a Review of Regulatory Approaches and Research Methods

open access: yesБезопасность и риск фармакотерапии
INTRODUCTION. Ophthalmotoxicity assessment of potential drugs is a highly meaningful element of preclinical trials that reflects modes of action and pharmacological effects of a chemical compound on the eyes in topical and systemic use. However, there is
L. V. Naumenko   +2 more
doaj   +1 more source

Identifying customer expectations is key to evidence based service delivery [PDF]

open access: yes, 2010
As librarians and information professionals we share a common rationale: to deliver enhanced services for our customers. The importance of this is self-evident - if we don’t have customers we don't have a job. We therefore put our services at peril if we
Booth, A, McKnight, S
core   +2 more sources

Dissecting the role of TRPV1 in detecting multiple trigeminal irritants in three behavioral assays for sensory irritation

open access: yesF1000Research, 2013
Polymodal neurons of the trigeminal nerve innervate the nasal cavity, nasopharynx, oral cavity and cornea. Trigeminal nociceptive fibers express a diverse collection of receptors and are stimulated by a wide variety of chemicals.
Cj Saunders   +4 more
semanticscholar   +1 more source

Are there common academic library customer values? [PDF]

open access: yes, 2008
: Purpose – This paper endeavours to provide answers to the following questions: Is there a correlation between what library customers value and the questions asked in benchmarking satisfaction surveys?
McKnight, S
core   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas   +18 more
wiley   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma   +5 more
wiley   +1 more source

Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice. [PDF]

open access: yesPLoS ONE, 2015
Addition of menthol to cigarettes may be associated with increased initiation of smoking. The potential mechanisms underlying this association are not known.
Michael A Ha   +7 more
doaj   +1 more source

IRRITANT COMPOUNDS: RESPIRATORY IRRITANT GASES [PDF]

open access: yesMilitary Medical Science Letters, 2014
Summary Respiratory irritants are substances which can cause inflammation or other adverse reactions in the respiratory system (lungs, nose, mouth, larynx and trachea) after being inhaled. Depending on the type and amount of irritant gas inhaled, victims can experience symptoms ranging from minor respiratory discomfort to acute airway and lung injury ...
Jiří Patočka, Kamil Kuča
openaire   +1 more source

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