Results 1 to 10 of about 436,348 (295)

Low irritation potential of tazarotene 0.045% lotion: Head-to-head comparison to adapalene 0.3% gel and trifarotene 0.005% cream in two studies

Journal of Dermatological Treatment, 2023
Background Irritation with topical retinoids presents a significant impediment to acne treatment adherence. Two studies assessed the irritation potential of tazarotene 0.045% lotion versus adapalene 0.3% gel and trifarotene 0.005% cream.
Zoe D. Draelos
doaj   +1 more source

​​Irritating Bowels​: Attention and Everyday Management of Gut Trouble in Denmark

Medicine Anthropology Theory, 2023
Irritable bowel syndrome (IBS) constitutes an irritating and embarrassing problem for an estimated 11–16% of the Danish population. Based on long-term ethnographic fieldwork, this article explores how young and middle-aged people diagnosed with IBS ...
Camilla Brændstrup Laursen
doaj   +1 more source

Dermal sensitization, safety, and tolerability of triple-combination clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel from three clinical trials

Journal of Dermatological Treatment, 2023
Background Using a three-pronged acne treatment approach—combining an antibiotic, antimicrobial agent, and retinoid—may provide greater efficacy than monad or dyad treatments.
Zoe D. Draelos, Emil A. Tanghetti, Leon H. Kircik, Neal Bhatia, Joshua A. Zeichner, Jeffrey L. Sugarman, Linda Stein Gold   +6 more
doaj   +1 more source

Evaluation of Two Novel Hydantoin Derivatives Using Reconstructed Human Skin Model Episkin^TM: Perspectives for Application as Potential Sunscreen Agents

Molecules, 2022
This study aimed to assess two novel 5-arylideneimidazolidine-2,4-dione (hydantoin) derivatives (JH3 and JH10) demonstrating photoprotective activity using the reconstructed human skin model EpiskinTM. The skin permeability, irritation, and phototoxicity
Karolina Słoczyńska, Justyna Popiół, Agnieszka Gunia-Krzyżak, Paulina Koczurkiewicz-Adamczyk, Paweł Żmudzki, Elżbieta Pękala   +5 more
doaj   +1 more source

Evaluation of Properties of Dexamethasone Eye Drops

European Pharmaceutical Journal, 2023
During the development of medicinal forms (eye drops), it is necessary to consider several parameters, so that the medicine is nonirritating to the eye and, at the same time, has the desired effect.
Matušová D., Gluštíková P., Špaglová M., Krchňák D.   +3 more
doaj   +1 more source

Toxicity Assessment of Resveratrol Liposomes-in-Hydrogel Delivery System by EpiVaginal^TM Tissue Model

Pharmaceutics, 2022
The natural polyphenol resveratrol (RES) has shown great potential as an antimicrobial, including against microbes associated with vaginal infections.
May Wenche Jøraholmen, Pauliina Damdimopoulou, Ganesh Acharya, Nataša Škalko-Basnet   +3 more
doaj   +1 more source

Chitosan/Solid-Lipid Nanoparticles Hybrid Gels for Vaginal Delivery of Estradiol for Management of Vaginal Menopausal Symptoms

Pharmaceuticals, 2023
Hormonal replacement therapy is the mainstay treatment to improve quality of life and reduce mortality. With the increasing number of young women with early menopause, women now live longer (increased life expectancy).
Heba A. Abou-Taleb, Zeinab Fathalla, Demiana M. Naguib, Adel Al Fatease, Hamdy Abdelkader   +4 more
doaj   +1 more source

Working during the COVID-19 pandemic: Demands, resources, and mental wellbeing

Frontiers in Psychology, 2023
The aim of this study was to investigate the relationship between working conditions at the start of the COVID-19 pandemic (spring 2020) and employees’ mental wellbeing. According to the Job Demands-Resources (JD-R) model, work intensification, increased
Tabea Eleonore Scheel, Lydia Bendixen, Jakub Procházka, Daniela Acquadro Maran   +3 more
doaj   +1 more source

The effect of variation of tetrahydropentagamavunon-0 concentration in lotion and emulgel formula toward acute dermal irritation study

Journal of Advanced Pharmaceutical Technology & Research, 2021
Tetrahydropentagamavunon-0 (THPGV-0) is a curcumin metabolite analog which known has a higher antioxidant activity than Vitamin E. This compound has been formulated in lotion as antiaging cosmetics, but the irritation effect is unknown yet.
Ritmaleni, Dina Suci Susilo Putri, Tia Wulandari, Abdul Karim Zulkarnain, Mimiek Murrukmihadi   +4 more
doaj   +1 more source

ANGST und VERDRUSS. Sprachliche Expressivität im soziokulturellen Kontext [PDF]

Linguistische Treffen in Wrocław, 2023
The insights and findings of the neurosciences and cognitive sciences in particular have brought new momentum to emotion research. The hitherto underestimated social contexts of emotions have become the focus of research interest.
Hanna Kaczmarek
doaj   +1 more source