Results 211 to 220 of about 44,820 (294)

Impact of response shift on change in patient-reported outcomes: a systematic review. [PDF]

open access: yesQual Life Res
Verdam MGE   +5 more
europepmc   +1 more source

Tutorial on Analyzing Patient‐Reported Outcome Measures in Clinical Development

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Patient‐reported outcomes (PROs) are now considered essential components of clinical development and regulatory assessment. Despite their widespread collection, PRO data remain under‐utilized, with analyses often limited to descriptive summaries or single time‐point comparisons that fail to capture the richness, longitudinal structure, and ...
Krina Mehta   +4 more
wiley   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6584-6594, August 2026.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas   +11 more
wiley   +1 more source

Medication Non‐Adherence in First Episode Psychosis: A Systematic Review

open access: yesEarly Intervention in Psychiatry, Volume 20, Issue 8, August 2026.
ABSTRACT Objective Despite the efficacy of antipsychotics, medication non‐adherence remains common among individuals with a First Episode of Psychosis (FEP). Methods A systematic review was conducted in accordance with the PRISMA 2020 guidelines to summarise the existing evidence base regarding the reasons, attitudes, and beliefs underlying both ...
James Hunt, Anna Georgiades
wiley   +1 more source

Clinical Utility of Infrared Thermography in Pediatric Patients: A Systematic Review of Surgical and Nonsurgical Applications.

open access: yesJ Indian Assoc Pediatr Surg
Kumar B   +7 more
europepmc   +1 more source

Cross-cultural adaptation and validation of a Moroccan Arabic version of the Hooked on Nicotine Checklist. [PDF]

open access: yesFront Public Health
Moutawakkil SG   +4 more
europepmc   +1 more source

Faking Resistance of Forced‐Choice and Single‐Statement Personality Measures: Stress‐Testing With Humans and Generative AI

open access: yesInternational Journal of Selection and Assessment, Volume 34, Issue 3, August 2026.
ABSTRACT A major concern with personality assessment in high‐stakes settings is test‐takers misrepresenting (“faking”) their personalities. Although test developers have adopted difficult‐to‐fake forced‐choice (FC) formats, generative artificial intelligence (AI) now offers test‐takers a highly sophisticated “test‐coach,” and yet it is unclear how ...
Chet Robie   +6 more
wiley   +1 more source

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