Results 191 to 200 of about 700,093 (271)

Patient and public involvement and engagement in target trial emulation framework: a scoping review protocol. [PDF]

BMJ Open
Egesa IJ, Baldwin FD, Wells M, Maden M, Mbizvo GK, Marson AG, Tudur-Smith C.   +6 more
europepmc   +1 more source

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová, Shahar Azar, Bella Agranovich, Ifat Abramovich, Saveliy Kirillov, Alina Nemirovski, Saja Baraghithy, Inbar Plaschkes, Emmanuelle Merquiol, Alexander Rouvinski, Galia Blum, Liad Hinden, Joseph Tam   +12 more
wiley   +1 more source

Methods and mechanisms for measuring and monitoring outcomes from newborn bloodspot screening: a scoping review.

Health Technol Assess
Scandrett K, Dinnes J, Morrison B, Coombe A, Agarwal R, Asare IA, Mead P, De Souza A, Elliman D, Lombardo S, Marshall J, Taylor-Phillips S, Takwoingi Y.   +12 more
europepmc   +1 more source

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda, Marcos M. Villegas‐Rojas, Isaac Pérez‐Segura, Maricela Espino‐Cambrón, Daniel Martinez‐Fong, Luis O. Soto‐Rojas   +5 more
wiley   +1 more source

Early-Onset Myocardial Infarction in Adults Under 45: A Review of Five Cases. [PDF]

Cureus
Matta S, Isaac T, Lazarescu R, Zafar M, Prabhu H.   +4 more
europepmc   +1 more source

Childhood Fractional Exhaled Nitric Oxide Predicts Incident Allergic Rhinitis in Adolescence and Young Adulthood

Allergy, EarlyView.
Chin‐Hung Wang, Jing‐Long Huang, Hui‐Ju Tsai, Hsin‐Yi Huang, Yu‐Lun Tseng, Tsung‐Chieh Yao   +5 more
wiley   +1 more source

Prevalence and Sociodemographic Variation of Allergic Diseases in Australia: Findings From the Australian National Health Survey

Clinical &Experimental Allergy, EarlyView.
Using data from 17,093 participants in the 2022 Australian National Health Survey, this study is the first to report nationwide prevalence estimates for allergic rhinitis (23.9%), food allergy (7.0%), drug allergy (5.2%), eczema (1.6%) and diagnosed asthma (10.8%) across Australia.
Yichao Wang, Jennifer J. Koplin, Janet M. Davies, Constance H. Katelaris, Debra J. Palmer, Jason A. Trubiano, Joy Lee, Michaela Lucas, Michael O′Sullivan, Sandra Vale, Sheryl van Nunen, Troy Wanandy, Dianne E. Campbell, Kirsten P. Perrett, Rachel L. Peters   +14 more
wiley   +1 more source

Robo‐Saber: Generating and Simulating Virtual Reality Players

Computer Graphics Forum, EarlyView.
Abstract We present the first motion generation system for playtesting virtual reality (VR) games. Our player model generates VR headset and handheld controller movements from in‐game object arrangements, guided by style reference gameplay examples. We train on the large BOXRR‐23 dataset and apply our framework on the popular VR game Beat Saber.
N. H. Kim, M. J. Liu, J. Lehtinen, P. Hämäläinen, J. F. O'Brien, X. B. Peng   +5 more
wiley   +1 more source

‘We Are Only Playing’: Reflections on the Pandemic's Effects on Immigrant Preschoolers' Mentalisation and Play During the Sand Play Workshops

Children &Society, EarlyView.
ABSTRACT Mentalisation and symbolisation are important processes to support children in understanding their lived experience. By expressing what is most salient to them through pretend play, children can normally develop their capacity to mentalise and symbolise, which helps them cope with adversity.
Caroline Beauregard
wiley   +1 more source

Evaluating the empirical basis for threat attribution in the IUCN Red List

Conservation Biology, EarlyView.
Abstract Understanding the impacts of different threats on species is key to successful conservation interventions and policies. The International Union for Conservation of Nature (IUCN) assesses threats to species, and the organization's Red List of Threatened Species is a key conservation tool.
Ena Humphries, Isaac M. Smith, Mark Ziebell, Charlotte M. Probst, Neil Carter, Brian C. Weeks   +5 more
wiley   +1 more source