ABSTRACT Artificial protein design enables the creation of stable scaffolds beyond those evolved in nature. Incorporation of native functional motifs into de novo scaffolds provides a promising strategy to mimic natural interactions while altering structural frameworks.
Hakuto Miyoshi +7 more
wiley +1 more source
Seamless analysis of liquid samples by coupling a thermal desorption chip with ion mobility spectrometry. [PDF]
Fechner A +6 more
europepmc +1 more source
Temporal Dilution: Chemotherapy, Capitalism, and the Making of Cancer Time in Colombia
ABSTRACT Through the ethnographic case of a man undergoing chemotherapy for prostate cancer at a hospital in Colombia, this article examines how chemotherapy schedules make toxicity clinically manageable while imposing rhythms that many patients cannot sustain. It develops an analytic framework centered on three interrelated temporal dynamics: temporal
Camilo Sanz
wiley +1 more source
Frustrated and Concerned: Understanding Antipathy Towards Clients Who Engage in Nonsuicidal Self-Injury in Australian Mental Health Practitioners. [PDF]
Wishart M, Gates J, Fisher A, Hallam KT.
europepmc +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the bloodâbrain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Backbone and side chain <sup>1</sup>H, <sup>13</sup>C and <sup>15</sup>N chemical shift assignment of the cargo-recognition domain MOTH of human TANGO1. [PDF]
Auch J, Peddinghaus AC, Stoll R.
europepmc +1 more source
Brief Access Delay and Interruption to Reduce Social Media Use: Is it Effective?
ABSTRACT Social media use is widespread among young adults, with many individuals frequently engaging with platforms that provide immediate access to entertainment, social interaction, and personalized content. Social media detoxification broadly refers to planned reductions, interruptions, or temporary restrictions in social media use.
Harley Ditzler +3 more
wiley +1 more source
Efficacy and safety of belimumab versus rituximab for refractory immune thrombocytopenia in patients with connective tissue disease. [PDF]
Yuan X +6 more
europepmc +1 more source
This study examined how urbanization and lateral hydrological gradients shape the functional structure and functional rarity of spontaneous plants in urban river corridors in Changde, China. Using field surveys, functional trait analysis, and structural equation modeling, we found that urbanization mainly affected communities through indirect pathways,
Yuxuan Li, Yuandong Hu, Yumeng Zhang
wiley +1 more source

