Results 11 to 20 of about 4,865 (116)
ABSTRACT Malignant otitis externa (MOE), necrotizing otitis externa (NOE), or skull base osteomyelitis (SBO) is a severe ear infection, primarily caused by Pseudomonas aeruginosa with 5%–20% of cases due to fungal species. Fungal NOE affects immunocompromised patients.
Mohammed A. Elkrim Saad Mohammed +8 more
wiley +1 more source
ABSTRACT Background Chronic and recalcitrant dermatophytosis has become increasingly problematic in dermatology practice, largely due to emerging antifungal resistance, affecting not only terbinafine but also azoles. Among the causative agents, Trichophyton indotineae has emerged as a key pathogen associated with treatment failure, extensive disease ...
Murat Durdu +8 more
wiley +1 more source
ABSTRACT Fusarium spp. are opportunistic fungal pathogens, with an increasing incidence of infection observed in immunocompromised populations. Due to the non‐specific clinical manifestations of cutaneous Fusarium infections, they are often misdiagnosed or overlooked.
Yulin Wang +9 more
wiley +1 more source
Graphical abstract for a case of a 26‐year‐old female with advanced HIV disease, cryptococcal meningitis, and co‐infection with pulmonary aspergillosis. Both co‐infections were successfully treated with the novel oral lipid nanocrystal formulation of amphotericin B (MAT2203).
Enock Kagimu +6 more
wiley +1 more source
Histopathological analysis of an infiltrative nasal lesion, diagnostic for Extranodal NK/T cell lymphoma (ENKTL), with its characteristic angiotropism, angiodestruction, and immunohistochemical staining, including positivity for EBER. ABSTRACT Extranodal NK/T‐cell lymphoma is an aggressive malignancy, rare in Western populations, that can mimic benign ...
Leonor Dias +5 more
wiley +1 more source
ABSTRACT Ziftomenib, a potent, highly selective, oral menin inhibitor, has demonstrated significant clinical benefit and deep responses in relapsed and/or refractory (R/R) nucleophosmin 1‐mutated (NPM1‐m) acute myeloid leukemia (AML) patients. Here we present data from analyses conducted to characterize ziftomenib pharmacokinetics (PK) in healthy ...
Amitava Mitra +5 more
wiley +1 more source
ABSTRACT Background Aspergillus fumigatus resistance to triazole antifungals poses an increasing global health concern. Moreover, the cross‐resistance between azole antifungal agents used in clinical settings and those applied in agriculture has become an important emerging issue.
Dality Keffelen de Barros Rodrigues +9 more
wiley +1 more source
ABSTRACT This case reports a patient with chronic obstructive pulmonary disease who developed immune checkpoint inhibitor‐associated pneumonia following immunotherapy, complicated by invasive pulmonary aspergillosis. Such cases are rare and pose diagnostic challenges in clinical practice. The successful diagnosis and treatment of this patient provide a
Shifeng Lin
wiley +1 more source
An orthorhombic polymorph of isavuconazole
The title compound C 22 H 17 F 2 N 5 OS (systematic name: 4-{2-[(2 R ,3 R )-3-(2,5 ...
Ben, Anna, Chęcińska, Lilianna
openaire +2 more sources

