Results 171 to 180 of about 1,184,407 (410)

Role of complement factor D in cardiovascular and metabolic diseases

Frontiers in Immunology
In the genesis and progression of cardiovascular and metabolic diseases (CVMDs), adipose tissue plays a pivotal and dual role. Complement factor D (CFD, also known as adipsin), which is mainly produced by adipocytes, is the rate-limiting enzyme of the ...
Yingjin Kong, Yingjin Kong, Naixin Wang, Naixin Wang, Zhonghua Tong, Zhonghua Tong, Dongni Wang, Dongni Wang, Penghe Wang, Penghe Wang, Qiannan Yang, Qiannan Yang, Xiangyu Yan, Xiangyu Yan, Weijun Song, Weijun Song, Zexi Jin, Zexi Jin, Maomao Zhang, Maomao Zhang   +19 more
doaj   +1 more source

Inhibitor of apoptosis-stimulating protein of p53 inhibits ferroptosis and alleviates intestinal ischemia/reperfusion-induced acute lung injury

Cell Death and Differentiation, 2020
Yingchuan Li, Yongmei Cao, Jian-Men Xiao, Jiawei Shang, Qin Tan, Feng Ping, Weifeng Huang, Fang Wu, Haijun Zhang, Xiaoping Zhang   +9 more
semanticscholar   +1 more source

The Role of Silicon Technology in Organ‐On‐Chip: Current Status and Future Perspective

Advanced Materials Technologies, EarlyView.
This review explores the potential of silicon micro‐nanofabrication technologies in advancing organ‐on‐chip systems. The integration of actuation and sensing modalities, highlight emerging technologies is discussed for combining silicon‐based and polymer‐based components, and emphasize the need for robust, high‐throughput, and customizable organ‐on ...
Frøydis Sved Skottvoll, Enrique Escobedo‐Cousin, Michal Marek Mielnik   +2 more
wiley   +1 more source

Aging-associated Alteration in the Cardiac MIF-AMPK Cascade in Response to Ischemic Stress [PDF]

, 2008
An important role for a macrophage migration inhibitory factor (MIF)-AMP-activated protein kinase (AMPK) signaling pathway in ameliorating myocardial damage following ischemia/reperfusion has been described. An aging-associated reduction in AMPK activity
Erin Lane, Heng Ma, Ji Li, Jingying Wang, Jun Ren, Lin Leng, Richard Bucala, Wenkui Wang   +7 more
core   +1 more source

Ventricular Arrhythmias and K+ Transfer during Myocardial Ischemia and Intervention with Procaine Amide, Insulin, or Glucose Solution* [PDF]

, 1967
Timothy J. Regan, Maureen A. Harman, Patrick H. Lehan, William M. Burke, Henry A. Oldewurtel   +4 more
openalex   +1 more source

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, EarlyView.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

The Safety and Efficacy of Intravascular Lithotripsy in the Treatment of Severe Coronary Artery Calcification in 261 Cases: A Retrospective Study

Health Science Reports
Background Coronary artery calcification is strongly linked to factors such as advanced age, dyslipidemia, and chronic kidney disease. Severe coronary artery calcification significantly elevates the complexity and risk of percutaneous coronary ...
Tiankun Wu, Honghui Yang, Guian Xu, Qingman Li, Lijie Zhu, Yapan Yang, Tingjie Yang   +6 more
doaj   +1 more source

Prevalence and prognostic significance of DNMT3A- and TET2- clonal haematopoiesis-driver mutations in patients presenting with ST-segment elevation myocardial infarction

EBioMedicine, 2022
Summary: Background: Clonal haematopoiesis driven by mutations in DNMT3A or TET2 has recently been identified as a new risk factor for cardiovascular disease.
Shengfang Wang, Sining Hu, Xing Luo, Xiaoyi Bao, Ji Li, Minghao Liu, Ying Lv, Chen Zhao, Ming Zeng, Xi Chen, Amanda Unsworth, Sarah Jones, Thomas W. Johnson, Stephen J. White, Haibo Jia, Bo Yu   +15 more
doaj  

Bee Better: The Role of Honey in Modern Wound Care

Advanced Therapeutics, EarlyView.
The use of honey as a wound care agent is controversial but paradoxically increasingly popular. Honey possesses relevant antimicrobial properties and can modulate the immune system. The wound healing properties of honey likely depend on its composition and varies across wound types.
Léo‐Paul Tricou, Natalie Guirguis, Sarah Djebbar, Benjamin R. Freedman, Simon Matoori   +4 more
wiley   +1 more source

Corrigendum: C1q/TNF-Related Protein 9 Attenuates Atherosclerosis by Inhibiting Hyperglycemia-Induced Endothelial Cell Senescence Through the AMPKα/KLF4 Signaling Pathway

Frontiers in Pharmacology, 2021
Gang Wang, Gang Wang, Baihe Han, Baihe Han, Ruoxi Zhang, Qi Liu, Qi Liu, Xuedong Wang, Xuedong Wang, Xingtao Huang, Xingtao Huang, Dandan Liu, Dandan Liu, Weishen Qiao, Weishen Qiao, Mengyue Yang, Mengyue Yang, Xing Luo, Xing Luo, Jingbo Hou, Jingbo Hou, Bo Yu, Bo Yu   +22 more
doaj   +1 more source