Results 191 to 200 of about 1,184,407 (410)
Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury
Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang+5 more
wiley +1 more source
Ischemia and reperfusion—from mechanism to translation
H. Eltzschig, T. Eckle
semanticscholar +1 more source
Nanotherapy for Neural Retinal Regeneration
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu+11 more
wiley +1 more source
Ranolazine Reduces Ca\u3csup\u3e2+\u3c/sup\u3e Overload and Oxidative Stress and Improves Mitochondrial Integrity to Protect Against Ischemia Reperfusion Injury in Isolated Hearts [PDF]
Ranolazine is a clinically approved drug for treating cardiac ventricular dysrhythmias and angina. Its mechanism(s) of protection is not clearly understood but evidence points to blocking the late Na+ current that arises during ischemia, blocking ...
Aldakkak, Mohammed+4 more
core +1 more source
Schematic representation of mechanisms by which the 3‐D sustained‐release culture carrier prevents accumulation of ROS by continuously releasing C‐176@PDA‐NPs and inhibiting the cGAS‐STING activated by sudden hypoxia, thereby preventing ferroptosis and promoting differentiation in SSCs and ultimately attenuating IVDD progression.
Liwen Luo+12 more
wiley +1 more source
Coronary CTA and Quantitative Cardiac CT Perfusion (CCTP) in Coronary Artery Disease [PDF]
We assessed the benefit of combining stress cardiac CT perfusion (CCTP) myocardial blood flow (MBF) with coronary CT angiography (CCTA) using our innovative CCTP software. By combining CCTA and CCTP, one can uniquely identify a flow limiting stenosis (obstructive-lesion + low-MBF) versus MVD (no-obstructive-lesion + low-MBF.
arxiv
Long-Term Results of Endarterectomy of the Internal Carotid Artery for Cerebral Ischemia and Infarction [PDF]
Albert Heyman+3 more
openalex +1 more source
Antibody‐drug conjugates are among the fastest‐growing drugs in oncology. It combines the potent killing activity of small molecular drugs and the high specific targeting of antibody drugs. Our in vitro and in vivo studies suggest that anti‐CD147 ADC Mehozumab‐DM1 potently inhibits hepatocellular carcinoma, and combining CD147‐ADCs and targeted therapy
Wan Huang+16 more
wiley +1 more source
Prediction of cerebral blood volume change after resuscitation from hypoxic-ischemic insult for newborn piglets [PDF]
Neonatal hypoxic-ischemic encephalopathy (HIE) is a significant cause of neonatal mortality and developmental disabilities. It has been revealed that the temporal behavior of the cerebral blood volume (CBV) carries information on the degree of hypoxia-ischemia. CBV can be estimated by means of near-infrared spectroscopy.
arxiv