Results 191 to 200 of about 965,659 (315)

Mitochondrial Dysfunction and Myocardial Ischemia-Reperfusion: Implications for Novel Therapies.

Annual Review of Pharmacology and Toxicology, 2017
E. Lesnefsky, Qun Chen, B. Tandler, C. Hoppel   +3 more
semanticscholar   +1 more source

Advanced Biomaterial Delivery of Hypoxia‐Conditioned Extracellular Vesicles (EVs) as a Therapeutic Platform for Traumatic Brain Injury

Advanced Science, EarlyView.
This research introduces a novel approach to enhance neuroregeneration following Traumatic Brain Injury (TBI). Extracellular Vesicles (EVs) are isolated from human neural progenitor cells under hypoxic conditions, leading to enhanced expression of neurogenic and angiogenic factors.
Joshua B. Stein, Songzi Zhang, Eun Ji Roh, Jeffrey Luo, Meizi Chen, Hyunjun Jang, Li Ling Goldston, Brandon Conklin, Inbo Han, Ki‐Bum Lee   +9 more
wiley   +1 more source

Safe time thresholds for temporary artery occlusion and surgical approach side strategy in ACOM aneurysm surgery. [PDF]

Sci Rep
Preuss-Hernandez C, Geiger P, Ortler M, Petrova L, Krigers A, Thomé C, Petr O.   +6 more
europepmc   +1 more source

Characteristic of the cerebral cortex microcirculation after ischemia

, 2017
О. П. Горшкова, В. Н. Шуваева   +1 more
openalex   +2 more sources

Ischemia preconditioning is neuroprotective in a rat cerebral ischemic injury model through autophagy activation and apoptosis inhibition [PDF]

, 2013
Deyu Xia, W. Li, Hao Qian, Shutong Yao, J.G. Liu, X.K. Qi   +5 more
openalex   +1 more source

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

Stroke, 2012
Xiaoming Hu, Peiying Li, Yanling Guo, Haiying Wang, R. Leak, Songela Chen, Yanqin Gao, Jun Chen   +7 more
semanticscholar   +1 more source

Sympathetic Activation Promotes Kidney Fibrosis in Mice via Macrophage‐Derived N2ICD‐Enriched Extracellular Vesicles

Advanced Science, EarlyView.
Norepinephrine/α2B‐adrenoceptor axis promotes the secretion of Notch2 intracellular domain (N2ICD)‐enriched extracellular vesicles (EVs) from macrophages. These EVs deliver N2ICD into fibroblasts, thereby inducing their activation. Deletion of Notch2 or α2B‐AR in macrophages disrupts N2ICD‐enriched EV formation and alleviates kidney fibrosis in mice ...
Huiwen Ren, Yayan Hou, Chengsen Mu, Yinghong Zheng, Yuanyang Wang, Shumin Guo, Lu Wang, Wenlong Shang, Zhuming Yin, Cheng Dong, Yongsheng Chang, Bin Zhou, Renjie Chai, Ying Yu, Yujun Shen   +14 more
wiley   +1 more source

Exogenous phosphatidylserine protects against mesenteric ischemia-reperfusion with associated Akt/mTOR pathway upregulation. [PDF]

Sci Rep
Hamaneh AM, Ghasemi M, Mehrabi MM, Ashtari S, Nejati F, Kazemzadeh H, Goudarzi R, Tavangar SM, Dehpour AR, Partoazar A.   +9 more
europepmc   +1 more source

The Association Between Spontaneous Hyperventilation, Delayed Cerebral Ischemia, and Poor Neurological Outcome in Patients with Subarachnoid Hemorrhage [PDF]

, 2015
Craig A. Williamson, Kyle M. Sheehan, Renuka Tipirneni, Christopher Roark, Aditya S. Pandey, B. Gregory Thompson, Venkatakrishna Rajajee   +6 more
openalex   +1 more source

Tie2‐Dependent Mechanisms Influence Leptomeningeal Collateral Dynamics and Reperfusion Following Stroke

Advanced Science, EarlyView.
This work demonstrates that endothelial EphA4 limits Tie2 activation and curbs leptomeningeal collateral expansion after ischemic stroke. Pharmacological activation of Tie2 by an Ang‐1 mimetic or genetic loss of EphA4 stimulates collateral vessel growth, improves cerebral perfusion, and enhances neurological recovery.
Alexandra M. Kaloss, Caroline de Jager, Kennedie Lyles, Nathalie A. Groot, Jackie Zhu, Yu Lin, Michael Chen, Hehuang Xie, John B. Matson, Michelle H. Theus   +9 more
wiley   +1 more source