Results 291 to 300 of about 1,184,407 (410)

CNPY2 Aggravates Renal Tubular Cell Ferroptosis in Diabetic Nephropathy by Regulating PERK/ATF4/CHAC1 Pathway and MAM Integrity

open access: yesAdvanced Science, EarlyView.
Canopy FGF signaling regulator 2 (CNPY2) which is contributed to ERS is upregulated in the renal tubules of patients with diabetic nephropathy (DN). Mechanistically, CNPY2 may regulate ferroptosis and MAM integrity in renal tubular epithelial cells through PERK/ATF4/CHAC1 pathway, thereby promoting the progression of DN.
Jingfang Chen   +9 more
wiley   +1 more source

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

open access: yesAdvanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong   +15 more
wiley   +1 more source

Exosomes: an innovative therapeutic target for cerebral ischemia-reperfusion injury. [PDF]

open access: yesFront Pharmacol
Yang Y   +6 more
europepmc   +1 more source

Intraaortic Balloon Pumping for Control of Recurrent Myocardial Ischemia [PDF]

open access: bronze, 1973
Herman K. Gold   +5 more
openalex   +1 more source

Identification of NIBAN2‐Regulated RUNX2 Alternative Splicing Presents Novel Strategies for Antagonizing Osteoporosis

open access: yesAdvanced Science, EarlyView.
NIBAN2 interacts with the HNRNPU‐cored spliceosome complex and alters its components to regulate the alternative splicing of RUNX2, which ultimately cause an increase in functional RUNX2 (nuclear localization sequence complete) but a decrease in dysfunctional Runx2 (exon 6‐exclusive) isoforms to reinforce osteoblast differentiation.
Sheng Zhang   +9 more
wiley   +1 more source

A case of left main coronary artery to pulmonary fistula associated with vasospastic angina. [PDF]

open access: yesJ Surg Case Rep
Shirakura K   +11 more
europepmc   +1 more source

Graded global ischemia and reperfusion. Cardiac function and lactate metabolism. [PDF]

open access: bronze, 1977
Carl S. Apstein   +4 more
openalex   +1 more source

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