Results 231 to 240 of about 886,706 (266)

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Gastrointestinal complications of cocaine use: a narrative literature review. [PDF]

Front Gastroenterol (Lausanne)
Qasim A, Dasan SLAM, Veena F, Kandhi S, Patel H.   +4 more
europepmc   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Prevalence and Predictors of Hypercoagulable Disorders in Patients With Concomitant Acute Limb Ischemia and Ischemic Stroke: A Cross-Sectional Study. [PDF]

Cureus
Islam MA, Saha S, Islam MM, Irfan Subhan K, M Habibullah G.   +4 more
europepmc   +1 more source

Acute mesenteric ischemia following ischemic stroke: a rare sequential embolic event managed with Ethiopia's first endovascular intervention: Retraction. [PDF]

Ann Med Surg (Lond)
europepmc   +1 more source

Risk factors profile and outcomes of stroke in low resources settings: a prospective and multicentric study in a sub-Saharan Africa country. [PDF]

Front Neurol
Sebastião D, Lucas E, Lamborne P, Francisco A, Gonçalves M, Fresta M, de Oliveira AJM.   +6 more
europepmc   +1 more source

Mendelian randomization reveals the causal relationship between cholecystectomy and ischemic stroke. [PDF]

BMC Neurol
Xiao Y, Zhao Z, Liu J.
europepmc   +1 more source

White matter hyperintensity radiomics predicts 90-day diffusion-weighted imaging-confirmed acute ischemic stroke after diffusion-weighted imaging-negative transient ischemic attack: preliminary findings from a retrospective machine-learning study. [PDF]

Front Med (Lausanne)
Liu L, Lyu Y, Li Z, Zhou Y.
europepmc   +1 more source