Results 151 to 160 of about 67,239 (252)

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Transient ischemic attack caused by cerebral ergotism

Arquivos de Neuro-Psiquiatria, 2015
Gustavo Andrés Gaye Saavedra, Federico Preve, Silvana Albisu, Mariana Legnani   +3 more
doaj   +1 more source

Risk of Ischemic Stroke After Transient Ischemic Attack in Patients Receiving Comprehensive Versus Noncomprehensive Diagnostic Workup: A Systematic Review and Meta-Analysis. [PDF]

J Am Heart Assoc
Hejazian SS, Shahjouei S, Sadr AV, Vemuri A, Bahrami S, Abedi V, Zand R.   +6 more
europepmc   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Outcomes of Watchman device implantation in atrial fibrillation patients contraindicated for long-term anticoagulation: a single-center experience. [PDF]

Am J Cardiovasc Dis
Ghumman GM, Kalsoom S, Salman F, Noman A, Kanaan T, Meenakshisundaram C, Alo M, Zafrullah F, Alo S, Ali SS, Taleb M.   +10 more
europepmc   +1 more source

Oral Microbiota: Findings, Classification, Clinical Significance, and Therapeutic Interventions for Human Systemic Diseases

iMetaMed, EarlyView.
Oral microbiota: findings, classification, clinical significance, and therapeutic interventions for human systemic diseases ABSTRACT The oral microbiota is an ecological community of commensal, symbiotic, and pathogenic microorganisms that colonizes the oral cavity.
Miao Zhang, Meihang Du, Wenjiang Zhang, Renhuan Huang, Wanting Li, Tongqi Li, Junping Bai, Ning Zhang, Jungang Chen, Jing Zhou, Bing Wang, Liwei An, Hideaki Kagami, Yiming Zhang   +13 more
wiley   +1 more source

Acute ischemic stroke or TIA despite DOAC treatment: the contribution of DOAC plasma levels to understand pathophysiological mechanisms. [PDF]

Ther Adv Neurol Disord
Rust M, Gözalan M, Nikoubashman O, Wiesmann M, Imöhl M, Schulz JB, Reich A, Pinho J.   +7 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Impact of Insertable Cardiac Monitor-Detected Atrial Fibrillation on Future Ischemic Events Following Cryptogenic Stroke. [PDF]

JACC Adv
Bharucha R, Kim J, Alsheikh-Kassim M, Korada SK, Alfaro-Franco C, Xiong Y, Curtis AB.   +6 more
europepmc   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source