Adrenergic Control of P2Y6 Receptor‐Dependent Phagocytosis in Rodent and Human Microglia
Adrenergic signaling through ADRB2 modulates phagocytosis in microglia. Crosstalk between ADRB2 and P2Y6 receptors conserved in rodent and human microglia. ADRB2 activation inhibits both P2Y6 function and gene expression. ABSTRACT Microglia, the resident immune cells of the central nervous system (CNS), are in constant survey of their environment ...
Thomas Deluc+10 more
wiley +1 more source
Low-Density Lipoprotein Cholesterol Level, the Lower the Better? Analysis of Korean Patients in the Treat Stroke to Target Trial. [PDF]
Kwon H+15 more
europepmc +1 more source
Transient ischemic attack caused by cerebral ergotism
Gustavo Andrés Gaye Saavedra+3 more
doaj +1 more source
Left atrial appendage occlusion procedure and antithrombotics: less may be enough for lower risk patients: A single-center observational study. [PDF]
Kim MR+8 more
europepmc +1 more source
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
Prevalence of Stroke and Associated Risk Factors in Patients With Atrial Fibrillation: A Cross-Sectional Study. [PDF]
Gul N+9 more
europepmc +1 more source
Research progress of neurovascular units involved in ischemic stroke
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang+4 more
wiley +1 more source
Perioperative Anticoagulation and Risk Assessment: Building a Bridge Over a STREAM. [PDF]
Harrison A, Rayamajhi S.
europepmc +1 more source
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou+6 more
wiley +1 more source
Factors associated with oral anticoagulant non-use at first ischemic stroke in atrial fibrillation: A nationwide study. [PDF]
Vilpponen M+12 more
europepmc +1 more source