Results 211 to 220 of about 1,279,230 (303)

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source

Patent foramen ovale closure versus medical therapy for prevention of recurrent ischemic events in patients with cryptogenic stroke or transient ischemic attack and documented patent foramen ovale: a systematic review and network meta-analysis of randomized controlled trials and observational studies. [PDF]

Front Cardiovasc Med
Deng Y, An D, Xiong X, Zhou Z, Liu X, Xiang Y.   +5 more
europepmc   +1 more source

Association Between Deep Gray Matter Iron Deposition Dysregulation and Cognitive Performance in Type 2 Diabetes Mellitus Patients: A Quantitative Susceptibility Mapping Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Type 2 diabetes (T2DM) heightens cognitive impairment risk, yet the mechanisms remain unclear. Hyperglycemia‐induced iron dysregulation in deep gray matter (DGM) nuclei may be a crucial mechanism. Purpose To investigate DGM iron deposition in T2DM using Quantitative Susceptibility Mapping (QSM) and determine its association with ...
Kun Wang, Jiahe Wang, Ziyu Diao, Xin Tan, Shijun Qiu, Jie An   +5 more
wiley   +1 more source

Implantable Cardiac Monitoring for Atrial Fibrillation Detection in Patients with Stroke: A Systematic Review and Meta-Analysis. [PDF]

NeuroSci
Alkhamis NM, Almohammed HA, Khan TN, Alzahrani JH, Alsalboud LA, Alzahrani RT, Alseni HA, Mufti AM, Alghourab LH, Abuhaimed TF, Alshabaan MM, Alsubaie ME, Jamlalail MA, Alnaaim SA.   +13 more
europepmc   +1 more source

Efficacy and safety of dual antiplatelet treatment up to 72 hours after mild ischemic stroke or transient ischemic attack in patients with established cardiovascular disease. [PDF]

Neurotherapeutics
Xia Z, Gao Y, Chen W, Johnston SC, Amarenco P, Bath PM, Wang X, Gao P, Yan H, Wang T, Yang Y, Zhang Y, Wang Y, Wang Y, Pan Y.   +14 more
europepmc   +1 more source

Severity of periodontitis and risk of ischemic stroke: A systematic review and meta‐analysis

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a prevalent chronic inflammatory disease with a systemic inflammatory burden and is implicated with vascular pathology. This systematic review and meta‐analysis evaluates the association between varying severities of periodontitis and ischemic stroke with various diagnostic criteria.
Steven Sitt, Chloe J. Chang, Chin‐Wei Wang   +2 more
wiley   +1 more source

Medical trauma in context: Recognizing and addressing medically induced posttraumatic stress disorder in adults

Journal of Traumatic Stress, EarlyView.
Abstract Potentially traumatic medical events (PTMEs) occur across acute and chronic illness trajectories, such as invasive procedures, intensive care, and life‐threatening diagnoses. Emerging evidence suggests that approximately 20% of individuals exposed to PTMEs develop posttraumatic stress disorder (PTSD).
Reneé El‐Gabalawy, Sarah A. Stoycos, Nicholas Schumann, Keisha‐Gaye N. O'Garo, Sacha McBain   +4 more
wiley   +1 more source

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source

Hemodynamic Significance of APEXCT Coronary Angiography Combined With Dynamic CT Myocardial Perfusion Imaging in Assessing Restenosis After Coronary Stenting

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to evaluate the hemodynamic significance of in‐stent restenosis (ISR) by using a combined anatomical‐functional approach with photon‐counting CT coronary angiography (APEX‐CT CTA) and dynamic CT myocardial perfusion imaging (CT‐MPI). We prospectively enrolled 239 symptomatic patients at least 9 months after PCI.
Liang‐Shi Wang, Tian Bai, Ji‐Zhou Yan, Peng‐Yu Guan, Li‐Juan Wen, Hong Guo, Tian‐Yu Zhang   +6 more
wiley   +1 more source