Results 211 to 220 of about 76,994 (304)

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño   +6 more
wiley   +1 more source

Prioritizing Modifiable Risk Factors for Cardiovascular Diseases in Adults With Hypertension: A Prospective Cohort Study

open access: yesMed Research, EarlyView.
This study examined the relative contributions of modifiable risk factors to cardiovascular diseases in adults with hypertension. More favorable risk factor profiles were consistently associated with lower risks across all outcomes. Beyond blood pressure, nicotine exposure showed comparatively larger population attributable fractions.
Shengtao Wei   +10 more
wiley   +1 more source

Quantifying Cardiac, Respiratory, and Low Frequency Components of CSF Motion From fMRI Inflow Effects

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Cerebrospinal fluid (CSF) flow oscillations have emerged as a potentially important marker related to brain clearance, but their acquisition often relies on specialized imaging MRI sequences. The purpose of this work was to enable quantitative assessment of CSF flow associated with cardiac, respiratory, and low‐frequency cycles using ...
Pontus Söderström   +5 more
wiley   +1 more source

Post‐recanalization administration of rapamycin improves functional outcome and reduces infarct size in a rat model of ischemic stroke

open access: yesNeuroprotection, EarlyView.
Experimental design and main findings of the study. Transient middle cerebral artery occlusion was induced for 90 min in rats, followed by intravenous administration of rapamycin or vehicle at the time of recanalization. Functional outcome (Garcia scale and adhesive removal test), magnetic resonance imaging‐based infarct volume assessment, and cerebral
Anna M. Schneider   +4 more
wiley   +1 more source

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