Results 241 to 250 of about 107,429 (283)

Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons

Small Science, EarlyView.
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong, Yanyi Peng, Lingyue Zhang, Bo Xiao, Mengqi Zhang   +4 more
wiley   +1 more source

Sex and racial differences in prevalence and clinical characteristics of people living with LDLR and PCSK9 familial hypercholesterolemia genetic variants: Data from the All of Us Research program. [PDF]

Am J Prev Cardiol
Osei J, Razavi AC, Quyyumi AA, Eapen DJ, Sun YV, Khoury MJ, Sperling L.   +6 more
europepmc   +1 more source

Sphingosine‐1‐Phosphate Receptor Modulators for the Treatment of Ulcerative Colitis: A Narrative Review Focusing on Safety

United European Gastroenterology Journal, EarlyView.
ABSTRACT Ulcerative colitis is a chronic immune‐mediated inflammatory disease of the colon that causes considerable morbidity and increases the risk of colorectal cancer. Several targeted therapies have been developed for moderate‐to‐severe ulcerative colitis, significantly improving its management.
Massimo C. Fantini, Diego Centonze, Giovanni Giacobazzi, Silvia Benemei, Emanuele Romeo   +4 more
wiley   +1 more source

Statin initiation and early stroke recurrence in the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke Trial (POINT) trial population. [PDF]

J Stroke Cerebrovasc Dis
Azizi E, Prabhakaran S, Brorson JR.
europepmc   +1 more source

Gastric dilatation secondary to incarceration through a gastrosplenic omental rent in a dog

Veterinary Record Case Reports, EarlyView.
Abstract A 2‐year‐old, entire, female Dogue de Bordeaux presented with inappetence and abdominal distension. Radiographs revealed gastric dilatation and malpositioning. Given the absence of classical signs of gastric dilatation and volvulus, a medical approach was elected. After 24 hours, the dog's condition deteriorated.
Clara Galvani, Francesca Saponaro, Giacomo Galvani, Arrigo Galvani, Giliola Spattini   +4 more
wiley   +1 more source

Predicting Cognitive Impairment in Elderly Patients with HFpEF: Development of a Simple Clinical Risk Score. [PDF]

J Clin Med
Arnautu SF, Bernad BC, Korpos IG, Tomescu MC, Andor M, Jianu CD, Arnautu DA.   +6 more
europepmc   +1 more source

Comparison of Patent Foramen Ovale Closure vs Medical Therapy for the Prevention of Recurrent Cryptogenic Stroke: A Systematic Review. [PDF]

J Saudi Heart Assoc
Hamodat O, Almuzainy S, Yahya R, Koniali S.   +3 more
europepmc   +1 more source

Empowerment and mobile technology in the detection and treatment of main cardiovascular risk factors of patients with ischemic stroke or transient ischemic attack: a protocol for a multicenter randomized controlled trial (CARDIOSTROKE). [PDF]

Trials
Lumikari T, Putaala J, Pirinen J, Kerola A, Sibolt G, Granroth-Wilding H, Pakarinen S, Lehto M, Nieminen T.   +8 more
europepmc   +1 more source

Evaluation of systemic immune-inflammation index and systemic inflammation response index in the differentiation of acute Ischemic stroke and transient Ischemic attack. [PDF]

Malawi Med J
Yilmaz M, Uslu MF, Atescelık M, Atilgan FA.   +3 more
europepmc   +1 more source

Return to Work After Ischemic Stroke in Young Adults: A Multicenter Cohort Study, Systematic Review, and Meta-Analysis. [PDF]

J Am Heart Assoc
Kwok GYR, Yeong N, Law M, Kang ZL, Achar A, Lim XY, Ng MBJ, Teo YH, Tan SML, Ho JSY, Marmin M, Hassan F, Chia MLJ, Wong LYH, Sia CH, Sharma VK, Yeo LLL, Ahmad A, Tan BYQ.   +18 more
europepmc   +1 more source