Results 61 to 70 of about 69,480 (258)

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Transient ischemic attack is a multidisciplinary problem

Неврология, нейропсихиатрия, психосоматика, 2012
The paper discusses the issues associated with the definition of the concept «transient ischemic attack» (TIA) and with the prognosis of cerebrovascular disease after prior TIA.
Valentina Vladimirovna Gudkova, T V Shanina, E A Petrova, L V Stakhovskaya   +3 more
doaj   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Young Stroke Survivors With No Early Recurrence at High Long‐Term Risk of Adverse Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Approximately 8% to 21% of strokes affect adults aged 5× that of young controls (hazard ratio, 5.2; 95% CI, 2.8–9.4), compared with a 30% increase at 5 years for older patients (hazard ratio, 1.3; 95% CI, 1.3–1.4).
Jodi D. Edwards, Moira K. Kapral, M. Patrice Lindsay, Jiming Fang, Richard H. Swartz   +4 more
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Ataque transitorio de isquemia, el heraldo del ictus Transient ischemic attack: the herald of stroke

Revista Cubana de Investigaciones Biomédicas, 2012
Introducción: el ataque transitorio de isquemia constituye una parte fundamental de la enfermedad cerebrovascular, en muchas ocasiones no bien diagnosticado por su corta duración, lo difícil de ver y sus variadas manifestaciones clínicas.
Javier Sánchez López, Isis Rodríguez Ribalta, Martha Beatriz Díaz Dehesa   +2 more
doaj  

Risk Factors Associated with Recurrent Strokes in Young and Elderly Patients: A Hospital-based Study

International Journal of Gerontology, 2015
Background: Recurrent stroke is often devastating, and can cause severe disability or death. Risk factors associated with recurrent strokes unrelated to atrial fibrillation have been well identified; however, it remains to be further elucidated whether ...
Guang-Rong Fu, Wei-Qiang Yuan, Wan-Liang Du, Zhong-Hua Yang, Na Fu, Hua-Guang Zheng, Zi-Xiao Li, Yu-Ming Huang, Yu-Mmei Zhang, Guang-Zheng Dai, Hua-Bing Wang, Jian-Mei Li, Jing-Dong Yi, Qing-Biao Yang, Hong-Jun Tian, Li-Nan He, Geng-Yu Li, Jia-Li Zhang, Li-Mei Yang, Yan Gao, Zi-Wei Fu   +20 more
doaj   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source

Cross‐Platform Proteomics and Machine Learning Algorithms Nominate Plasma Biomarkers of Stroke Diagnosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Blood‐based biomarkers for stroke subtyping could improve triage in emergency settings. We used cross‐platform proteomics to identify plasma biomarkers differentiating major stroke diagnostic groups.
Shubham Misra, Wooyoung Eric Jang, Sebastian Sanchez, Aditya Natu, Prateek Kumar, Michael Liu, Anmol Kaur, Victor Torres Lopez, Pinar Caglayan, Rolando Garcia‐Milian, Caroline M. Watson, Michael R. Frankel, Guido J. Falcone, Lauren H. Sansing, Srikant Rangaraju   +14 more
doaj   +1 more source