Results 21 to 30 of about 75,701 (257)

Mitochondrial Transfer Induced by Adipose-Derived Mesenchymal Stem Cell Transplantation Improves Cardiac Function in Rat Models of Ischemic Cardiomyopathy

Cell Transplantation, 2023
Although mesenchymal stem cell transplantation has been successful in the treatment of ischemic cardiomyopathy, the underlying mechanisms remain unclear.
Daisuke Mori, Shigeru Miyagawa, Takuji Kawamura, Daisuke Yoshioka, Hiroki Hata, Takayoshi Ueno, Koichi Toda, Toru Kuratani, Miwa Oota, Kotoe Kawai, Hayato Kurata, Hiroyuki Nishida, Akima Harada, Toshihiko Toyofuku, Yoshiki Sawa   +14 more
doaj   +1 more source

Multimodality Imaging in Ischemic Cardiomyopathy [PDF]

Current Cardiovascular Imaging Reports, 2014
Cardiac multimodality (hybrid) imaging can be obtained from a variety of techniques, such as nuclear medicine with single photon emission computed tomography (SPECT) and positron emission tomography (PET), or radiology with multislice computed tomography (CT), magnetic resonance (MR) and echography.
Prior JO, Farhad H, Muller O
openaire   +3 more sources

Comparison of Benefits from Cardiac Resynchronization Therapy between Patients with Ischemic Cardiomyopathy and Patients with Idiopathic Dilated Cardiomyopathy [PDF]

Journal of Tehran University Heart Center, 2009
Background: Cardiac resynchronization therapy (CRT) is an effective treatment for patients with moderate to severe heart failure. However, 20-30% of patients remain non-responders to CRT.
Talia Alenabi, Ali Moezi, Ahmad Yaminisharif, Saeed Sadeghian, Gholamreza Davoodi, Ali Bozorgi, Ali Kazemi Saeid, Maryam Khoshnevis, Ali Kazemi Saeid, Ali Bozorgi, Gholamreza Davoodi, Saeed Sadeghian, Ahmad Yaminisharif, Ali Moezi, Talia Alenabi, Maryam Khoshnevis   +15 more
doaj   +2 more sources

Searching for Intrinsic Causality between Colonic Dysbiosis and Non-Ischemic Cardiomyopathy: A Mendelian Randomization-Based Analysis

Journal of Cardiovascular Development and Disease, 2023
Objective: Little is known about gut microbiota (GM) and cardiomyopathy. Their causal relationship was explored using two-sample Mendelian randomization (TSMR) performed by R software.
Bin Qi, Zhi-Jie Yang, Nan Huang, Wen-Bo Zheng, Chun Gui   +4 more
doaj   +1 more source

Specifics of Diabetic Cardiomyopathy in the Cases of Concomitant Cardiovascular Diseases: Clinical and Ultrastructural Examinations

Mìžnarodnij Endokrinologìčnij Žurnal, 2016
Introduction. The concept of diabetic cardiomyopathy was first proposed by S. Rubler et al. more than 100 years ago, but this diagnosis іs rarely used by clinicians because of the existence of such co-morbidities as ischemic heart disease and arterial ...
Yu.H. Kyyak, H.Yu. Kyyak, O.Yu. Barnett
doaj   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Left ventriculoplasty for ischemic cardiomyopathy [PDF]

European Journal of Cardio-Thoracic Surgery, 2001
In order to treat ischemic cardiomyopathy, which is defined as non-aneurysmal diffuse akinetic left ventricle with chronic heart failure following myocardial infarction, the mid-term effect of the endoventricular circular patch plasty (EVCPP) was studied.EVCPP has been performed on 54 patients (46 men and eight women with a mean age of 61 years) during
H, Suma, T, Isomura, T, Horii, K, Hisatomi   +3 more
openaire   +2 more sources

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source