Results 211 to 220 of about 578,524 (300)

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran, Mohammad Ali Omrani, Flory T. Muanda   +2 more
wiley   +1 more source

<i>APOE ε4</i> and ischemic heart disease in American Indian/Indigenous tribal Elders. [PDF]

Am Heart J Plus
Labounek R, Matheson MJ, Petersen AJ, Hansen A, Block AD, Strong C, Hill A, Kremer M, Robertson AJ, Maharaj V, Lakshminaryan K, Li D, Henderson JN, Nestrasil I, Lenglet C, Mantyh WG.   +15 more
europepmc   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Metabolic regulation for the treatment of ischemic heart disease with stem cells and extracellular vesicles. [PDF]

NPJ Cardiovasc Health
Liu S, Jin L, Zhang J, Zhang X, Shi Y, Tu Z, Xu J.   +6 more
europepmc   +1 more source

APOE genotype and the effect of statins on lipid outcomes: A meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim APOE genotype may affect statin therapy response. We conducted a meta‐analysis to update and quantify this association across various outcomes. Methods We searched seven databases (MEDLINE, Scopus, Web of Science, the Cochrane Library, APA PsycINFO, CINAHL Plus and ClinicalTrials.gov) on 9 May 2024.
Innocent G. Asiimwe, Tsegay Gebru, Andrea L. Jorgensen, Munir Pirmohamed, on behalf of the Multimorbidity Mechanism and Therapeutics Research Collaborative   +4 more
wiley   +1 more source

An integrated resource for ischemic heart disease defines hallmarks and heterogeneity across time and space. [PDF]

Acta Pharm Sin B
Wang T, Hu Y, Guo W, Li H, Wang M, Chen B, Bao H, Gao M, Li X, Chen Q, Shen M, Shao X, Liao J, Fan X.   +13 more
europepmc   +1 more source

Layered double hydroxides‐based nanozymes for effective biomedical applications: A review and future perspectives

BMEMat, EarlyView.
In this review, we introduced the preparation methods of LDHzymes and discussed their catalytic activity and mechanisms. Subsequently, the applications of LDHzymes in biomedical were discussed. Finally, potential future work on LDHzymes was proposed to better design these new types of nanozymes.
Jiawei Cui, Lu Zhang, Junyi Li, Yue Chen, Sheng Dai, Manfred F. Maitz, Ansha Zhao, Ping Yang   +7 more
wiley   +1 more source

Global trends in ambient particulate matter-attributable ischemic heart disease among the elderly (1990-2021). [PDF]

Front Cardiovasc Med
Zeng Y, Liu L, Huang G, Liu C, Lan X, Mou Y, Wang X, Liao B, Wan J.   +8 more
europepmc   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Does educational attainment modify the relationship between alcohol use and ischemic heart disease mortality? Evidence from the UK biobank. [PDF]

Nutr Metab Cardiovasc Dis
Martin T, Llamosas-Falcón L, Zhu Y, Rehm J, Probst C, Kilian C.   +5 more
europepmc   +1 more source