Results 81 to 90 of about 36,030 (232)

A Review of Nanoparticle‐Based Astrocyte Modulation in CNS Disorders: Evaluating the Underexplored Potential of Intranasal Delivery

Nano Select, Volume 7, Issue 1, January 2026.
Nanoparticle‐driven nose‐to‐brain drug delivery offers a noninvasive approach to bypass the blood–brain barrier (BBB) and directly modulate reactive astrocytes in CNS disorders. This review highlights biodegradable nanoparticles for astrocyte modulation, enhancing drug bioavailability, sustained release, and neuroinflammation control.
Senamile M. Dlamini, Gillian D. Mahumane, Pradeep Kumar, Yahya E. Choonara   +3 more
wiley   +1 more source

Adjustment and Characterization of an Original Model of Chronic Ischemic Heart Failure in Pig

Cardiology Research and Practice, 2010
We present and characterize an original experimental model to create a chronic ischemic heart failure in pig. Two ameroid constrictors were placed around the LAD and the circumflex artery.
Laurent Barandon, Joachim Calderon, Patricia Réant, Dominique Caillaud, Stéphane Lafitte, Xavier Roques, Thierry Couffinhal, Pierre Dos Santos   +7 more
doaj   +1 more source

Preoperative risk factors of emergency conversion to artificial circulation during off-pump coronary artery bypass grafting in patients with ischemic congestive heart disease

Вестник хирургии имени И.И. Грекова, 2020
INTRODUCTION.  Coronary  artery   bypass  surgery is  the  most   popular   method  of  surgical   treatment of  patients with chronic   heart   failure  of  ischemic  origin.
G. G. Khubulava, A. E. Sukharev, V. N. Kravchuk, A. M. Volkov, A. I. Lyubimov, E. A. Knyazev, A. S. Kusay, D. U. Romanovskiy, A. V. Birukov, V. I. Zvoznikov   +9 more
doaj   +1 more source

The effects of aetiology on outcome in patients treated with cardiac resynchronization therapy in the CARE-HF trial [PDF]

, 2008
Aims: Cardiac dyssynchrony is common in patients with heart failure, whether or not they have ischaemic heart disease (IHD). The effect of the underlying cause of cardiac dysfunction on the response to cardiac resynchronization therapy (CRT) is unknown ...
Andren, B, Blomstrom, P, Blomstrom-Lundqvist, C, CARE-HF Study Investigators,, Cleland, JGF, Freemantle, N, Lonnerholm, S, Remp, T, Wikstrom, G   +8 more
core   +2 more sources

Impact of mitral insufficiency on reoperative coronary artery surgery in ischemic cardiomyopathy patients? [PDF]

European Journal of Cardio-Thoracic Surgery, 2004
To determine the impact of mitral insufficiency on survival after reoperative coronary artery bypass grafting (CABG) in ischemic cardiomyopathy patients.We retrospectively studied 891 (Initial 708, Redo 183) consecutive CABG patients (1993-2002) with ejection fraction (EF) 35% or less.mean age=67.0+/-10.5 yrs, men=77.1%, EF=26.4+/-7.4%, mean CCS=3.47+/-
Nan, Wang, Saida, Campwala, Saied, Habibipour, Darren, Hodgins, Ramdas, Pai, Anees, Razzouk   +5 more
openaire   +2 more sources

The high-risk features among patients undergoing mitral valve operation for ischemic mitral regurgitation: The 3-strike scoreCentral MessagePerspective

JTCVS Open
Objective: Ischemic mitral regurgitation is prevalent and associated with high surgical risk. With the less-invasive option of transcatheter edge-to-edge repair, the optimal patient selection for mitral valve operation for ischemic mitral regurgitation ...
Makoto Mori, MD, PhD, Christina Waldron, BS, Sigurdur Ragnarsson, MD, Markus Krane, MD, Arnar Geirsson, MD   +4 more
doaj   +1 more source

The effect of cardiac resynchronization on morbidity and mortality in heart failure [PDF]

, 2005
Background: Cardiac resynchronization reduces symptoms and improves left ventricular function in many patients with heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony.
Cleland, John G.F., Daubert, Jean-Claude, Erdmann, Erland, Freemantle, Nick, Gras, Daniel, Kappenberger, Lukas, Tavazzi, Luigi   +6 more
core   +1 more source

Mid-term results of mitral valve reconstruction by using D-ring and C-flex systems in patients with degenerative mitral valve disease

Патология кровообращения и кардиохирургия, 2015
Objective. The purpose of the research was to compare early and mid-term results following mitral valve repair by using semirigid and flexible annuloplasty rings.Methods.
С. И. Железнев, А. В. Богачев-Пркофьев, А. В. Афанасьев, В. М. Назаров, И. И. Демин, А. М. Караськов   +5 more
doaj   +1 more source

Functional and Biomechanical Effects of the Edge-to-Edge Repair in the Setting of Mitral Regurgitation: Consolidated Knowledge and Novel Tools to Gain Insight into Its Percutaneous Implementation [PDF]

, 2014
Mitral regurgitation is the most prevalent heart valve disease in the western population. When severe, it requires surgical treatment, repair being the preferred option.
Faggian, Giuseppe, Onorati, Francesco, Puppini, Giovanni, Redaelli, Alberto, Sturla, Francesco, Votta, Emiliano   +5 more
core   +1 more source

Bridge to recovery with left ventricular assist device and mitral transcatheter edge-to-edge repair in cardiogenic shock due to acute ischemic mitral insufficiency: a novel option to treat patients without surgery or heart transplant.

Polish Archives of Internal Medicine, 2023
Maciej Bochenek, M. Kosowski, R. Przybylski, B. Barteczko-Grajek, M. Błaziak, W. Kuliczkowski   +5 more
semanticscholar   +1 more source