Results 51 to 60 of about 30,950 (253)

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

open access: yesAdvanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies   +14 more
wiley   +1 more source

Riparazione percutanea della valvola mitrale con Mitraclip nei pazienti con scompenso cardiaco avanzato e insufficienza mitralica funzionale: impatto clinico ed effetti sul rimodellamento cardiaco e sul profilo neurormonale. [PDF]

open access: yes, 2016
The role of percutaneous mitral valve repair (PMVR) in patients with advanced heart failure (HF) and functional mitral regurgitation (FMR) is unclear. The aim of this study was to assess the effects (PMVR) therapy on clinical outcomes , left ventricular (
Berardini, Alessandra <1981>
core   +1 more source

The Novel ACTC1 p.Gly50Ser Variant Is Associated With Arrhythmia and Secondary Features of HCM Without Hypertrophy

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The key diagnostic criterion for hypertrophic cardiomyopathy is the presence of otherwise unexplained hypertrophy. Current definitions of HCM rely on specific thresholds to establish a diagnosis, while guideline directed risk stratification algorithms take its magnitude into consideration.
Thomas D. Gossios   +9 more
wiley   +1 more source

TWEAK/Fn14 signaling drives oxidative cardiac injury in systemic lupus erythematosus: Evidence from patient biomarker studies, lupus mouse models, and cardiomyocyte assays

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/Fn14 signaling in SLE‐related cardiomyopathy and its potential as a ...
Yale Liu   +12 more
wiley   +1 more source

Intracardiac Calcification - An Interesting Chest X-ray Report. [PDF]

open access: yes, 2013
We report a case of chest X-ray finding of mitral annular calcification. Mitral annular calcification is a degenerative process involving the fibrous annulus of the mitral valve.
Anupama, N   +5 more
core  

Incidence and In‐Hospital Mortality of Ventricular Septal Rupture Following Acute Myocardial Infarction

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Ventricular septal rupture (VSR) is a rare but devastating complication of acute myocardial infarction (MI), associated with high mortality despite advances in reperfusion therapy. However, contemporary data examining national trends in VSR outcomes and the evolving role of mechanical circulatory support (MCS) in this population ...
Javier Fernandez   +8 more
wiley   +1 more source

Patient–valve mismatch: A comparison of mechanical versus biological prostheses in ischemic mitral patients undergoing chordal-sparing mitral valve replacement

open access: yesJournal of Medicine in Scientific Research, 2021
Background Chordal-sparing mitral valve replacement (MVR) is now preferred over downsized annuloplasty repair in treating chronic severe ischemic mitral regurgitation.
Ahmed S Ali   +2 more
doaj   +1 more source

Proportionate and Disproportionate Functional Mitral Regurgitation: A New Conceptual Framework That Reconciles the Results of the MITRA-FR and COAPT Trials [PDF]

open access: yes, 2019
Traditional approaches to the characterization of secondary or functional mitral regurgitation (MR) have largely ignored the critical importance of the left ventricle (LV).
Grayburn P. A., Packer M., Sannino A.
core   +1 more source

Long‐Term Impact of Prosthesis‐Patient Mismatch After Transcatheter Aortic Valve Replacement in Patients With Small Aortic Annuli

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Prosthesis‐patient mismatch (PPM) remains common following transcatheter aortic valve replacement (TAVR) and is associated with worse clinical outcomes. PPM is of particular concern in small aortic annuli (SAA). Aims To compare the incidence, predictors, and long‐term impact of PPM in SAA TAVR.
Itamar Loewenstein   +9 more
wiley   +1 more source

Association between the proportionality of functional mitral regurgitation and survival after mitral valve operationCentral MessagePerspective

open access: yesJTCVS Open
Objective: The concept of proportionate and disproportionate functional mitral regurgitation suggests that transcatheter edge-to-edge mitral repair may benefit patients with a smaller left ventricle relative to a higher regurgitant burden.
Makoto Mori, MD, PhD   +7 more
doaj   +1 more source

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