Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar +7 more
wiley +1 more source
The effects of sildenafil ciltrate on the lateral geniculate body of adult Wistar rats (Rattus norvegicus)- A histological study [PDF]
The histological effect of oral administration of sildenafil citrate (Viagra), commonly used as an aphrodisiac and for the treatment of erectile dysfunction on one of the visual relay centres namely the lateral geniculate body (LGB) of adult Wistar rat ...
Eweka, A, Eweka, AO
core +1 more source
Eletroretinograma de padrão reverso no diagnóstico e acompanhamento das afecções da via óptica anterior [PDF]
The pattern electroretinogram is an electrophysiological test that assesses the function of inner retinal layers, particularly the ganglion cells layer of retina, using a reversing checkerboard or grating pattern that produces no change in average ...
HOKAZONO, Kenzo +2 more
core +2 more sources
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen +14 more
wiley +1 more source
An Unforeseeable Complication; Posterior Ischemic Optic Neuropathy after Penetrating Injury to the Heart [PDF]
Trauma surgeons are currently encountering unusual adverse events after traumatic injuries. Ischemic optic neuropathy is a rare complication that may occur in trauma and burn patients that present in extremis and require massive resuscitation.
Joseph Eid, Brian Cronin, Susan Seman
doaj
Múltiplos defeitos localizados da camada de fibras nervosas em um paciente com glioma de nervo óptico no olho contralateral: relato de caso [PDF]
This case report describes a young non-glaucomatous patient with neurofibromatosis and previous history of optic nerve glioma, which developed multiple wedge-shaped retinal nerve fiber layer defects close to a chorioretinal scar in the fellow eye.
Lima, Verônica Castro +4 more
core +3 more sources
Nonarteritic Ischemic Optic Neuropathy
To describe the systemic and visual characteristics and prognosis in patients with nonarteritic ischemicoptic neuropathy (NAION) undergoing different treatments.Retrospective chart review was performed in Kaohsiung Veterans General Hospital patients from 1995-2005 with a clinical diagnosis of NAION, including nonarteritic anterior ischemic optic ...
Lin, Muh-Chiou +2 more
openaire +2 more sources
Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss
. ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao +9 more
wiley +1 more source
Background Neuromyelitis optica is a relapsing–remitting disease characterized by a recurrent attack of optic neuritis and transverse myelitis; sometimes associated with acute brainstem syndrome.
S. K. Jakaria Been Sayeed +4 more
doaj +1 more source
Corticosteroid therapy in patients with non-arteritic anterior ischemic optic neuropathy [Kortikosteroidi u liječenju bolesnika s nearteritičkom prednjom ishemičkom optičkom neuropatijom] [PDF]
Non-arteritic anterior ischemic optic neuropathy is one of the most common conditions affecting the optic nerve in the elderly. It may lead to severe visual loss.
Cerovski, Branimir +4 more
core

