Results 81 to 90 of about 483,267 (209)

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Bilateral anterior ischemic optic neuropathy after bilateral neck dissection

, 2010
María J Suárez-Fernández, Antonio Clariana-Martín, Enrique Mencía-Gutiérrez, Esperanza Gutiérrez-Díaz, Teresa Gracia-García-MiguelOphthalmology Department,
María J Suárez-Fernández, et al, Enrique Mencía-Gutiérrez, Antonio Clariana-Martín   +3 more
core  

Anterior ischemic optic neuropathy secondary to interferon alpha

Zdravniški Vestnik, 2005
Background: Anterior ischemic optic neuropathy rarely occurs with interferon alpha therapy. The mechanism by which interferon induces anterior ischemic optic neuropathy is unknown.Methods: A 62-year-old man presented with complaints of sudden severe loss
Stanka Godina-Kariž, Nives Avancini, Stojan Kariž   +2 more
doaj  

Recurrent subacute visual loss presenting in a 52-year-old Caucasian woman with chronic relapsing inflammatory optic neuropathy: a case report

Journal of Medical Case Reports, 2012
Introduction Chronic relapsing inflammatory optic neuropathy is a recently described form of recurrent isolated subacute optic neuropathy. The condition is highly responsive to systemic steroid treatment and prone to relapse on steroid withdrawal.
Samra Amrit, Ramtahal Jason
doaj   +1 more source

Anti‐obesity medications and incident ocular outcomes: A systematic review and network meta‐analysis

VIEW, EarlyView.
In this systematic review and network meta‑analysis of 140 studies, anti‑obesity medications showed heterogeneous ocular safety profiles. Semaglutide was associated with higher NAION risk (observational data), whereas dual/multi‑agonists and glucagon‐like peptide‐1 receptor agonists demonstrated favourable glaucoma and overall ocular outcomes ...
Linge Jian, Keke Zhang, Wenwen He, Yan Ke, Yi Lu, Xiangjia Zhu   +5 more
wiley   +1 more source

Sequential development of non-arteritic anterior ischemic optic neuropathy in a patient on hemodialysis

, 2017
Purpose: Non-arteritic anterior ischemic optic neuropathy (NA-AION) is typically a disorder of patients 50 years and older predisposed to the vascular and structural optic disc risk factors.
Jain, M, Parchand, MS, Babu, KR, Srinivasan, R   +3 more
core   +1 more source

Ischemic Optic Neuropathy: A Review of Current and Potential Future Pharmacotherapies

Pharmaceuticals
The treatment of arteritic anterior ischemic optic neuropathy (AAION), non-arteritic ischemic optic neuropathy (NAAION), and posterior ischemic optic neuropathy (PION) is a topic of ongoing research with mixed evidence on some pharmacotherapies and a ...
Omar Badla, Beshr Abdulaziz Badla, Amr Almobayed, Carlos Mendoza, Krishna Kishor, Sanjoy K. Bhattacharya   +5 more
doaj   +1 more source

Ischaemic Optic Neuropathy After Cardiac Surgery: A Systematic Review and Meta‐Analysis of Incidence and Risk Factors

ANZ Journal of Surgery, EarlyView.
Across 11 observational studies comprising 6 471 577 patients, the pooled incidence of ischaemic optic neuropathy after cardiac surgery was approximately 1.5 cases per 10 000 procedures. Coronary artery disease, peripheral vascular disease and anaemia were associated with increased odds of ION, although these findings should be interpreted in the ...
Daud Mutahar, Ammar Zaka, Amitouj S. Sidhu, Shahi Goswami, Aditi Singh, Jordan Ng, Brandon Stretton, Joshua G. Kovoor, Aashray K. Gupta, Stephen Bacchi, Weng Onn Chan, Celia Chen   +11 more
wiley   +1 more source

A case of anterior ischemic optic neuropathy associated with uveitis

, 2013
Michitaka Sugahara, Takayuki Fujimoto, Kyoko Shidara, Kenji Inoue, Masato Wakakura Inouye Eye Hospital, Tokyo, Japan Introduction: Here, we describe a patient who presented with anterior ischemic optic neuropathy (AION) and subsequently developed uveitis.
Sugahara M, Shidara K, Fujimoto T, Inoue K, Wakakura M   +4 more
core  

Nonarteritic Ischemic Optic Neuropathy [PDF]

, 2007
BackgroundTo describe the systemic and visual characteristics and prognosis in patients with nonarteritic ischemic optic neuropathy (NAION) undergoing different treatments.MethodsRetrospective chart review was performed in Kaohsiung Veterans General ...
Lin, Muh-Chiou, Hsu, Feng-Ming, Sheu, Shwu-Jiuan   +2 more
core   +1 more source