Results 51 to 60 of about 45,090 (263)
Clinical and Translational Discovery, 2023 Background Early diagnosis of hospitalized elderly patients with infectious stress hyperglycaemia (ISH) is clinically important, especially under the global coronavirus disease 2019 (COVID‐19) pandemic, as without timely prevention and effective ...
Kejing Zeng +9 more
doaj +1 more source
, 2014 Self-ish is a collection of essays surrounding the narrator's relationship to place, community, and family--the family one is born into and the family one chooses to create--and her evolving identity within these spaces. Essays include "The Cottage," which explores how the narrator's loss of innocence and feeling of community within her extended ...
O'Connor, Neely Bucknell, author +3 more
openaire +2 more sources
Advanced Science, EarlyView.CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin +17 more
wiley +1 more source
Detection of bacterial DNA by in situ hybridization in patients with decompensated liver cirrhosis
BMC Gastroenterology, 2017 Background Spontaneous bacterial peritonitis (SBP) is often difficult to diagnose because bacteria in ascites cannot be detected accurately by conventional culture.
Shingo Usui +6 more
doaj +1 more source
Advanced Science, EarlyView.Ex‐spRandom is a spatial transcriptomics platform that synergizes random‐primed chemistry with iterative hydrogel expansion. By physically decrowding the dense FFPE matrix, this scalable technology shatters the traditional resolution‐sensitivity barrier.
Shunji Zhang +7 more
wiley +1 more source
Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art
Advanced Intelligent Discovery, EarlyView.Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser +6 more
wiley +1 more source
P112 Influence of Cuff Blood Pressure Accuracy on Identification of Isolated Systolic Hypertension
Artery Research, 2020 Introduction: Isolated systolic hypertension (ISH) is the most common form of hypertension in older people. However, accurate identification of ISH may be hindered because cuff blood pressure (BP) underestimates systolic BP (SBP) and overestimates ...
Dean Picone +14 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu +4 more
wiley +1 more source
Applications in Plant Sciences, EarlyView.Abstract Premise Detecting clear tissue‐ and organ‐specific patterns of gene expression is key to understanding the genetic mechanisms that control plant development. In situ hybridization (ISH) of mRNA is one of the most precise, yet most challenging approaches to gene expression assays.
Brooklyn M. Anaya +3 more
wiley +1 more source
Animal Research and One Health, EarlyView.Integrated phenotypic, histological, transcriptomic, and validation analyses reveal that emaciation syndrome in Plectropomus leopardus is associated with intestinal structural damage, hepatic metabolic remodeling, and muscle protein degradation, highlighting coordinated multi‐tissue alterations underlying disease progression.
Zhihao Zhang +11 more
wiley +1 more source