Results 121 to 130 of about 62,631 (294)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu +14 more
wiley +1 more source
Tumor‐Derived Exosomal piR‐hsa‐28212 Promotes Lymphatic Metastasis in Breast Cancer
Cancer Science, EarlyView.Breast cancer–derived exosomal piR‐hsa‐28212 promotes lymphangiogenesis and lymph node metastasis by activating VEGFC/VEGFR3 signaling. It stabilizes TBX1 mRNA in lymphatic endothelial cells and METTL3 protein in tumor cells, enhancing VEGFR3 expression and VEGFC secretion.
Yafen Wang +7 more
wiley +1 more source
Insights Into the Interplay Between the Senescent Cells and Immune Cells. [PDF]
Aging CellKidney aging is associated with increased proximal tubular senescence and leukocyte infiltration. Senolytic treatment reduces senescent cell burden and overall immune cell infiltration. However, macrophages remain enriched around residual senescent cells.
Jaros M +7 more
europepmc +2 more sources
Child &Family Social Work, EarlyView.Abstract The COVID‐19 pandemic and related restrictions imposed in the UK had a significant impact on social work practice with children and young people. As has been widely reported, practitioners were deprived of multisensory information in their assessments and of opportunities to connect with children.
Heather Ellis, Ariane Critchley
wiley +1 more source
Child &Family Social Work, EarlyView.ABSTRACT A hive of recent policy and legislative activity in Australian family law has emphasized the importance of children's right to participate in decision‐making following parental separation. Yet a powerful tension persists between supporting children's right to participation and protecting children from parental conflict.
Georgina Dimopoulos +3 more
wiley +1 more source
Child &Family Social Work, EarlyView.ABSTRACT Many young people in out‐of‐home care (OOHC) encounter difficulties when attempting to access their personal histories in the form of photographs, report cards and other key identity memorabilia. As a result of frequent placement changes, limited continuity of relationships and the administrative nature of case files, the personal narratives ...
Laura Simpson Reeves +5 more
wiley +1 more source