Single‐nuclei RNA sequencing reveals heterogeneity within developing GnRH3 neurons in zebrafish
Abstract Gonadotropin‐releasing hormone (GnRH) is a central regulator of vertebrate reproduction regulating pituitary gonadotropins. In zebrafish, GnRH3 serves as the hypophysiotropic isoform. Its neurons develop by migrating from the nasal placode to the hypothalamus, forming several distinct subpopulations along the migratory path.
Yalong Sun +4 more
wiley +1 more source
The Evolution of Blood Pressure Thresholds and Targets over Time: A Historical Review. [PDF]
Flacco ME +8 more
europepmc +1 more source
ABSTRACT Background Sedation is a fundamental component of critical care and requires regular, accurate assessment to support its safe titration and minimise harm. International guidelines and local policy at the Wythenshawe Hospital's Cardiothoracic Critical Care Unit mandate hourly documentation of the Richmond Agitation‐Sedation Scale (RASS).
Lajos Szentgyorgyi +5 more
wiley +1 more source
Detection of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus in cull dairy cows with underlying respiratory and systemic disease. [PDF]
Righter DJ +12 more
europepmc +1 more source
Branch retinal artery occlusion due to patent foramen ovale in a teenager
Abstract This report demonstrates the diagnostic evaluation and clinical management of a 16‐year‐old girl who developed branch retinal artery occlusion secondary to patent foramen ovale. The goal is to increase awareness of this rare presentation in adolescents among clinicians, with a summary of the important clinical features, multimodal imaging ...
Jie Zu +4 more
wiley +1 more source
Clinicopathologic characteristics and genomic profiling of HER2-low advanced gastric or gastroesophageal junction cancer. [PDF]
Lee CK +11 more
europepmc +1 more source
Summary of the Differential associations of oxidative stress parameters with neuroendocrine markers and hemodynamic reactivity in acute mental stress‐induced adrenergic reactivity profiles Abstract Stress‐induced alpha (α)‐ and beta (β)‐adrenergic reactivity profiles relate to distinct neuroendocrine‐associated hemodynamic reactivity and ...
Dewald Naudé +4 more
wiley +1 more source
Collision Tumors Involving Metastatic Carcinoma and Plasma Cell Myeloma: Report of Two Cases. [PDF]
Ahmed AA +4 more
europepmc +1 more source
Retinoic acid (RA) regulates the positional identity of cranial neural crest cells (CNCCs) through the transcription factors Alx1 and Alx4. Upon receiving RA from the local environment, liganded RAR/RXR heterodimers activate the expression of Alx1 and Alx4, which promote the frontonasal identity of CNCCs and inhibit the first pharyngeal arch identity ...
Shuxuan Wu +7 more
wiley +1 more source
The significance of the WHO/ISH absolute cardiovascular risk prediction scores among recent stroke survivors in Ghana-Insights from the PINGS2 multicenter study. [PDF]
Bockarie A +19 more
europepmc +1 more source

