SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley +1 more source
From Molecular Visualization to Spatial Landscapes: Engineering the Next Generation of In Situ Hybridization. [PDF]
Li Z, Luo M, Zhu M, Bai Y.
europepmc +1 more source
Increased Amyloidogenic Neuronal Injury in HIV‐1–infected APP‐KI Alzheimer's disease mice
Abstract INTRODUCTION A higher incidence of dementia, including Alzheimer's‐like pathology, is observed in aged people living with human immunodeficiency virus‐1 (HIV‐1). However, mechanisms linking HIV‐1 to Alzheimer's disease (AD) pathology remain unclear, due to the lack of animal models that allow for concurrent studies of HIV‐1 and AD.
Shaurav Bhattarai +12 more
wiley +1 more source
Clinical analysis of prenatal diagnosis, ultrasound findings, and follow-up in 92 Turner mosaic fetuses: a retrospective analysis of 12-year experience. [PDF]
Luo X +10 more
europepmc +1 more source
Molecular Visualization of α-Proteobacterial RNA Using a Newly Developed Probe in Extracted Samples, Bacterial Cells, and Rice Root Tissues. [PDF]
Xia J, Muramatsu S, Maeda I.
europepmc +1 more source
Serum Levels of Thyroid Hormones in Relation to Breast Cancer Prognosis: A Multicentre Cohort Study
High free T3 levels at diagnosis are associated with good survival following breast cancer. ABSTRACT Thyroid function has been suggested to be associated with breast cancer risk, but not much is known about thyroid hormones as a potential prognostic factor for breast cancer. This study investigated the relation between thyroid hormones in breast cancer
Annie Brange +9 more
wiley +1 more source
Association analysis of weight-adjusted waist index with hypertension and its subtypes. [PDF]
Wu L +6 more
europepmc +1 more source
Integrated evaluation of Achillea biserrata extracts combining LC‐MS/MS phytochemical profiling, antioxidant, enzyme inhibitory, and antiproliferative assays with multivariate chemometric analyses (Pearson correlation, PCA, hierarchical clustering, and PLS regression), revealing phytochemicals associated with the observed biological activities (The ...
Zühal Bayrakçeken Güven +2 more
wiley +1 more source
Investigation of Epstein-Barr virus or human cytomegalovirus in pediatric gliomas: A retrospective single-center study from Tunisia. [PDF]
Missaoui N +10 more
europepmc +1 more source

