The diagnostic value of the circadian rhythm gene KLF10 in anxiety-depressive disorders and its neuroimmune regulatory mechanisms. [PDF]
Animal Model Exp MedThis graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Liu A, Guo W, Li J, Zhang T, Xu D.
europepmc +2 more sources
circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple-Negative Breast Cancer. [PDF]
Adv Sci (Weinh)CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Jin Y +17 more
europepmc +2 more sources
Nodular Fasciitis of the Parotid Gland Mimicking Pleomorphic Adenoma: Cytological Features of a Diagnostic Pitfall. [PDF]
Diagn CytopatholABSTRACT Nodular fasciitis (NF) is a self‐limiting mesenchymal neoplasm that typically occurs in the subcutaneous tissue of the extremities, trunk, and head and neck region; involvement of the parotid gland is very rare. The cytological features of NF can closely mimic those seen in salivary gland neoplasms, particularly pleomorphic adenoma (PA ...
Jin X +4 more
europepmc +2 more sources
Decorous lower bounds for minimum linear arrangement [PDF]
, 2011 Minimum Linear Arrangement is a classical basic combinatorial optimization problem from the 1960s, which turns out to be extremely challenging in practice.
Salazar, J J, Caprara, A, Letchford, A N
core +5 more sources
Insights Into the Interplay Between the Senescent Cells and Immune Cells. [PDF]
Aging CellKidney aging is associated with increased proximal tubular senescence and leukocyte infiltration. Senolytic treatment reduces senescent cell burden and overall immune cell infiltration. However, macrophages remain enriched around residual senescent cells.
Jaros M +7 more
europepmc +2 more sources
Wake-induced transverse vibration of two interfering cylinders in tandem arrangement : modelling and analysis [PDF]
, 2013 This paper discusses wake-induced transverse vibration of two interfering cylinders in tandem ...
Armin, Milad, Srinil, Narakorn
core +4 more sources
, 2018 We introduce a new family of hyperplane arrangements in dimension n≥3 that includes both the Shi arrangement and the Ish arrangement. We prove that all the members of a given subfamily have the same number of regions – the connected components of the ...
Duarte, Rui +1 more
core +2 more sources
Getting close-ish: A corpus-based exploration of -ish as a marker of approximation and vagueness [PDF]
, 2023 This paper investigates the approximative nature of -ish, which takes its origin in de-adjectival adjectives in Middle English and from there spreads to -ish-derivatives from a wide array of bases, in terms of both categoriality and complexity.
Matthias Matthias Eitelmann Eitelmann +3 more
core +1 more source
XAVFSIZ VA ZARARLI ISH SHAROITLARIDA ISH MUNOSABATLARINI TARTIBGA SOLISHNING XUSUSIYATLARI
, 2023 <p>Bu maqola xavfsiz va zararli ish sharoitlarida ish munosabatlarini tartibga solishning kritik ko'rinishlarini o'rganadi. U ishchilarning sog'ligini va xavfsizligini ta'minlashning ahamiyatini, bunday sharoitlarni tartibga solayotgan yasama kadri,
Xalmatov Musliddin Muxammatovich +1 more
core +1 more source
Phase Engineering of Atomically Precise Nanoclusters (APNCs) of Gold and Beyond
Advanced Materials, EarlyView.Engineering the structural phase of materials is of paramount importance for both fundamental research and practical applications. In this Review, we summarize the recent progress in controlling the phases of atomically precise nanoclusters (APNCs) of gold, silver and copper, as well as bimetallic systems. The phase‐enabled material properties of APNCs
Yitong Wang +4 more
wiley +1 more source