Results 161 to 170 of about 534,607 (317)

Negative Regulators of Rice Agronomic Traits: Functional Insights and Applications in Genome Editing‐Based Breeding

Plant Biotechnology Journal, EarlyView.
ABSTRACT Rice is the staple crop for more than half of the global population, and improving grain yield, grain quality, and stress resistance remain central goals of modern rice breeding. Among current precision breeding strategies, genome editing has created new opportunities for crop improvement, but its success depends heavily on the selection of ...
Wenhao Wu, Feng Jin, Huaxiang Xu, Ranran Liao, Zhongming Fang   +4 more
wiley   +1 more source

Successful Retreatment of Chronic Hepatitis C Virus Genotype 1A Infection With Glecaprevir/Pibrentasvir in a Pediatric Patient With Developmental Disorder. [PDF]

In Vivo
Ishikawa T, Fujii K, Sakakibara S, Odaira A, Susa M, Uchitsubo T, Soichiro O.   +6 more
europepmc   +1 more source

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

Experimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris, Anton Trask‐Marino, Alemayehu Jufar, Ashenafi H. Betrie, Adam Southon, Sally G. Hood, Rinaldo Bellomo, Abraham H. Hulst, Clive N. May, Connie P. C. Ow, Yugeesh R. Lankadeva   +10 more
wiley   +1 more source

MAPK ERK5 is a novel regulator of MHC-I in cancer cells. [PDF]

Cell Commun Signal
Viñas-Casas M, Lizcano JM.
europepmc   +1 more source

Whole‐body hot water immersion effect on cerebral haemodynamics and subsequent cerebrovascular reactivity to carbon dioxide

Experimental Physiology, EarlyView.
Abstract To test the hypothesis that hot water immersion (HWI) improves cerebrovascular function via shear‐mediated mechanisms, this study determined cerebrovascular reactivity to carbon dioxide (CVRCO2${\mathrm{CV}}{{\mathrm{R}}_{{\mathrm{C}}{{\mathrm{O}}_2}}}$) before and after 60 min of 39°C HWI and a 21°C air control (CON) in 15 healthy ...
Samuel F. Leaney, Ester Tommasini, Guto W. Hughes, Alison M. Shepherd, Nyah D. Kingdon, Justin S. Lawley, Geoff B. Coombs, Jonathan P. Moore, Samuel J. Oliver   +8 more
wiley   +1 more source

SNRPD2-mediated regulation of DDX39B splicing promotes endometrial cancer progression by suppressing the activation of CTSC cryptic exons. [PDF]

Cell Death Dis
Li Y, Chen Z, Liu Y, Gao Y, Pu Y, Gao Q, Gao F, Yang N, Li P.   +8 more
europepmc   +1 more source

Novel volume‐electron microscopic ultrastructural analysis of gastrointestinal excitability associated with calcium–activated chloride channels

The Journal of Physiology, EarlyView.
Abstract figure legend Immunohistochemistry, electrophysiology and pharmacology are useful tools for understanding protein and channel expression and physiological reactions of calcium‐activated chloride channels (CaCCs). Conventional transmission electron microscopy has provided useful 2‐D information on organelle arrangement, localization and ...
Hiromi Tamada
wiley   +1 more source

Doxorubicin induces ferroptosis in endometrial cancer by suppressing the MKK6/p38/CEBPB axis. [PDF]

J Transl Med
Zhang J, Wang Z, Li Y, Zhao P, Ren D, Lu X.   +5 more
europepmc   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

Activity-Selectivity of Flavonoid Derivatives in Endometriotic Cells. [PDF]

ACS Omega
Gomes KS, Coelho JA, Tesser PEH, Souza DCS, Silva ML, Ferreira EA, Lago JHG, Cerchiaro G.   +7 more
europepmc   +1 more source