Results 111 to 120 of about 66,017 (245)

TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation

The FEBS Journal, EarlyView.
TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...
Margherita Genitoni, Lucia Merolle, Agnese Razzoli, Eleonora Maurizi, Gaia Gavioli, Roberto Baricchi, Chiara Marraccini, Davide Schiroli   +7 more
wiley   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

The FEBS Journal, EarlyView.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa, Natsumi Matsushima, Soma Ishimine, Honoka Nakamoto, Hajime Hayakawa, Yoko Yasuno, Tetsuro Shinada, Hiroshi Kawaide, Tomokazu Ito, Hisashi Hemmi   +9 more
wiley   +1 more source

ANALISIS PENGENDALIAN KUALITAS PRODUK KARKAS AYAM MENGGUNAKAN DIAGRAM ISHIKAWA DI PT. ABC

Jurnal Humaniora Teknologi
Karkas Ayam yang merupakan salah satu produk kelolaan perusahaan PT ABC yang terkenal dengan kualitasnya yang baik. Hal ini ditunjang dengan penerapan SOP di perusahaan yang dilakukan secara berkesinambungan. SOP sendiri adalah salah satu alat untuk mengendalikan kualitas produk karkas ayam yang baik.
Almira Ulimaz, Halimatus Sa’diah, Jesi Yardani, Kurnia Dwi Artika, Wan Yuliyanti, Dewi Amelia Widiyastuti   +5 more
openaire   +1 more source

Illustrating the Relationship Between Accounting and Taxation – A Romanian Approach. The Ishikawa Diagram

LUMEN Proceedings, 2018
It can be stated that in Romania there is a clear dependence of taxation on accounting that one can argue biases the quality of the information provided by the accounting information system. In this paper the authors analyzed, by use of environmental analysis and different methodological methods several possible causes that conduct to the statement of ...
Cristina TIMOFTE COCA, Simona-Maria TANASA BRINZARU   +1 more
openaire   +2 more sources

Japan: Internal migration and population decline

The Geographical Journal, EarlyView.
Short Abstract Examining the interdependencies between internal migration and national population decline in Japan, this paper begins by analysing the impacts of internal migration on national fertility decline, for example, through the early post‐World War II flows from high‐fertility countrysides to low‐fertility cities. It then focuses on the way in
Tony Fielding
wiley   +1 more source

Analysis of Failure States of Transportation Vehicles Using the Ishikawa Diagram: A Case Study

Applied Sciences
This study focuses on analyzing transportation vehicles using Ishikawa diagrams to understand random events (fault conditions) in the operation of monitored transportation vehicles.
Ján Kováč, Tomáš Kuvik, Vladimír Mancel, Jozef Krilek   +3 more
doaj   +1 more source

The Culture Clash of AI Adoption in Lean Quality Management. Resolving the Tensions at Siemens Electronics Works Amberg

Information Systems Journal, EarlyView.
ABSTRACT Artificial intelligence (AI) brings great potential for manufacturers, but clashes with the established culture due to the unexplainable and opaque nature of the solutions it provides. Having little experience in AI and machine learning (ML), most manufacturing leaders experience barriers implementing AI.
Benjamin van Giffen, Gunter Beitinger, Helmuth Ludwig, Bill Schiano, Konstantin Schmidt, Jan vom Brocke   +5 more
wiley   +1 more source

RISK ASSESSMENT FOR COMPOUNDING OINTMENTS QUALITY BY ISHIKAWA DIAGRAM CONSTRUCTION [PDF]

FARMACIA, 2021
openaire   +1 more source

Perspectives of Older Patients on the Complexity of Medication Use

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Medication use complexity is associated with non‐adherence, hospitalizations, and lower quality of life. It is most frequently measured with the Medication Regimen Complexity Index (MRCI). This instrument estimates the complexity of a patient's medication regimen, taking into account the pharmaceutical dosage forms and routes ...
Charlotte M. Falke, Mariëlle F. J. Koolen, Samuel L. Timmer, Fatma Karapinar‐Çarkit, Marcel L. Bouvy, Antoine C. G. Egberts, Wilma Knol   +6 more
wiley   +1 more source

Corticotropin‐Releasing Hormone (CRH) in Murine Narcolepsy: What Do Genetic and Immune Models Tell Us?

Journal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy type 1 is a chronic sleep disorder of putative autoimmune aetiology, primarily caused by the loss of orexin‐producing neurons in the hypothalamus. An additional 88% reduction in corticotropin‐releasing hormone‐immunoreactive neurons of the paraventricular nucleus has been recently observed in post‐mortem brains of individuals with ...
J. Zhou, S. Melzi, A. L. Morel, B. Georges, T. E. Scammell, G. J. Lammers, R. Fronczek, C. Peyron   +7 more
wiley   +1 more source