Results 151 to 160 of about 1,850,478 (263)
Angewandte Chemie, EarlyView.Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
IEEE AccessIsing machines are specialized computers for finding the lowest energy states of Ising spin models, onto which many practical combinatorial optimization problems can be mapped. Simulated bifurcation (SB) is a quantum-inspired parallelizable algorithm for
Tomoya Kashimata +3 more
doaj +1 more source
Self‐Sensing Artificial‐Muscle‐Empowered Humanlike Perception, Interaction, and Positioning
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.The proposed self‐sensorized artificial muscle (SSAM) can sense its length change as small as 0.01 mm via a seamlessly integrated multi‐segment induction coil. The SSAM provides accurate length information regardless of its loadings, driving pressure, or muscle design, adequate for robust data‐driven feedback control.
Houping Wu +6 more
wiley +1 more source
Gain‐of‐Function Engineering of the NifEN Scaffold Into a Self‐Assembling Nitrogenase
Angewandte Chemie, EarlyView.From scaffold to enzyme: Systematic engineering of the cofactor maturation scaffold NifEN reconstructs the P→M electron relay along with cofactor coordination and proton gating at the S2B site, converting NifEN into a functional nitrogenase capable of ATP‐dependent N2 reduction both in vitro and in vivo.
Yimo Yang +4 more
wiley +2 more sources
A 50-spin surface acoustic wave Ising machine
Communications PhysicsTime-multiplexed spinwave Ising Machines have unveiled a route towards miniaturized and low-cost combinatorial optimization solvers but are constrained in the number of spins by nonlinear spinwave dispersion.
Artem Litvinenko +3 more
doaj +1 more source
Highly reconfigurable oscillator-based Ising Machine through quasiperiodic modulation of coupling strength. [PDF]
Sci Rep, 2023 Albertsson DI, Rusu A.
europepmc +1 more source
Exploiting Ferroelectric and Spintronic Dynamics for Neural Network Computation
Advanced Intelligent Systems, EarlyView.Ferroelectric and spintronic devices, relying on the control of polarization and magnetization, offer intrinsically fast, durable, energy‐efficient, and low‐latency building blocks for analog in‐memory computing. The hysteretic dynamics of an order parameter are leveraged to provide nonvolatile, multistate memory and nonlinear switching. Brain‐inspired
Dashiell Harrison +4 more
wiley +1 more source
A Scalable and Resource‐Efficient Pipelined p‐Computer for Probabilistic Ising Machines
Advanced Intelligent Systems, EarlyView.(a) Block diagram of the portfolio optimization problem: given M assets, the goal is to determine the optimal weights w that maximize the expected return (based on the mean historical assets return u), while minimizing the risk, quantified by the assets covariance matrix S.
Deborah Volpe +9 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.A distributed wireless sensing framework enables noninvasive monitoring of plant salinity stress through leaf reflectance measurements acquired with portable optical sensors. The collected data are processed using TinyML‐based neural network models deployed at the edge, enabling accurate, real‐time, and low‐cost classification of salinity levels, while
Ali Ahmad +4 more
wiley +1 more source
AI‐Based Immortality: The Ethical Advantage of the Aretai Approach
AI &Innovation, EarlyView.ABSTRACT The convergence of artificial intelligence, digital identity technologies, and biogerontological ambitions has produced a novel set of philosophical problems that have not yet been adequately addressed within mainstream bioethical discourse. Digital life extension—encompassing AI‐generated avatars, neural data preservation, mind uploading, and
Mirko Daniel Garasic
wiley +1 more source